Rabbit OSGIN1 Polyclonal Antibody | anti-OSGIN1 antibody

OSGIN1 Rabbit Polyclonal

Cat. Num. AAA7602260

• Gene Names: OSGIN1; BDGI; OKL38
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: OSGIN1; Polyclonal Antibody; OSGIN1 Rabbit Polyclonal; anti-OSGIN1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 477

• Applicable Applications for anti-OSGIN1 antibody: ELISA (EIA), Western Blot (WB)
• Immunogen: Oxidative stress induced growth inhibitor 1
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Western Blot (WB)

(mouse ovary tissue were subjected to SDS PAGE followed by western blot with MBS7602260 (OSGIN1 antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

• NCBI GI #: 33695101
• NCBI GeneID: 29948
• NCBI Accession #: NP_892026.1
• NCBI GenBank Nucleotide #: NM_182981.2
• Molecular Weight: – Da
• NCBI Official Full Name: oxidative stress-induced growth inhibitor 1
• NCBI Official Synonym Full Names: oxidative stress induced growth inhibitor 1
• NCBI Official Symbol: OSGIN1
• NCBI Official Synonym Symbols: BDGI; OKL38
• NCBI Protein Information: oxidative stress-induced growth inhibitor 1
• UniProt Protein Name: Oxidative stress-induced growth inhibitor 1
• Protein Family: Oxidative stress-induced growth inhibitor
• UniProt Gene Name: OSGIN1
• UniProt Synonym Gene Names: OKL38; huOKL38
• UniProt Entry Name: OSGI1_HUMAN

NCBI Description

This gene encodes an oxidative stress response protein that regulates cell death. Expression of the gene is regulated by p53 and is induced by DNA damage. The protein regulates apoptosis by inducing cytochrome c release from mitochondria. It also appears to be a key regulator of both inflammatory and anti-inflammatory molecules. The loss of this protein correlates with uncontrolled cell growth and tumor formation. Naturally occurring read-through transcription exists between this gene and the neighboring upstream malonyl-CoA decarboxylase (MLYCD) gene, but the read-through transcripts are unlikely to produce a protein product. [provided by RefSeq, Aug 2011]

Uniprot Description

OSGIN1: Regulates the differentiation and proliferation of normal cells through the regulation of cell death. Belongs to the OKL38 family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 16q23.3

Molecular Function: growth factor activity; oxidoreductase activity; protein binding

Biological Process: cell differentiation; multicellular organismal development; negative regulation of cell growth; positive regulation of apoptosis