Rabbit NT5E/CD73 Polyclonal Antibody | anti-NT5E/CD73 antibody
NT5E/CD73 Rabbit Polyclonal
Purification: Immunogen Affinity Purified
Purification: Immunogen Affinity Purified
IHC: 1:50-1:500
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human stomach cancer tissue slide using MBS7602111 (NT5E,CD73 Antibody) at dilution of 1:200)
Western Blot (WB)
(Jurkat cells were subjected to SDS PAGE followed by western blot with MBS7602111 (NT5E,CD73 antibody) at dilution of 1:1000)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
Uniprot Description
NT5E: Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Homodimer; disulfide-linked. Belongs to the 5'-nucleotidase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nucleotide Metabolism - pyrimidine; Phosphatase (non-protein); Nucleotide Metabolism - purine; Membrane protein, GPI anchor; EC 3.1.3.5; Membrane protein, integral; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide
Chromosomal Location of Human Ortholog: 6q14-q21
Cellular Component: cell surface; cytoplasm; membrane; plasma membrane
Molecular Function: 5'-nucleotidase activity; ferrous iron binding; nucleotide binding
Biological Process: adenosine biosynthetic process; AMP catabolic process; brain development; dephosphorylation; DNA metabolic process; leukocyte adhesion; negative regulation of inflammatory response; positive regulation of lipid biosynthetic process; purine nucleotide biosynthetic process; purine nucleotide catabolic process; pyrimidine nucleoside catabolic process; response to aluminum ion
Disease: Calcification Of Joints And Arteries
Research Articles on NT5E/CD73
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Product Notes
The NT5E/CD73 nt5e (Catalog #AAA7602111) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NT5E/CD73 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NT5E/CD73 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistichemistry (IHC). WB: 1:500-1:5000 IHC: 1:50-1:500. Researchers should empirically determine the suitability of the NT5E/CD73 nt5e for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NT5E/CD73, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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