Rabbit SURF4 Polyclonal Antibody | anti-SURF4 antibody
SURF4 Antibody (C-term)
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab); Surfeit locus protein 4; SURF-4; anti-SURF4 antibody
comprised of very tightly linked housekeeping genes that do not
share sequence similarity. The encoded protein is a conserved
integral membrane protein containing multiple putative
transmembrane regions. In eukaryotic cells, protein transport
between the endoplasmic reticulum and Golgi compartments is
mediated in part by non-clathrin-coated vesicular coat proteins
(COPs). The specific function of this protein has not been
determined but its yeast homolog is directly required for packaging
glycosylated pro-alpha-factor into COPII vesicles. This gene uses
multiple polyadenylation sites, resulting in transcript length
variation. The existence of alternatively spliced transcript
variants has been suggested, but their validity has not been
determined.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Mitrovic, S., et al. Mol. Biol. Cell 19(5):1976-1990(2008)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
NCBI and Uniprot Product Information
NCBI Description
This gene is located in the surfeit gene cluster, which is comprised of very tightly linked housekeeping genes that do not share sequence similarity. The encoded protein is a conserved integral membrane protein that interacts with endoplasmic reticulum-Golgi intermediate compartment proteins. Disruption of this gene results in reduced numbers of endoplasmic reticulum-Golgi intermediate compartment clusters and redistribution of coat protein I to the cytosol. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Uniprot Description
SURF4: May play a role in the maintenance of the architecture of the endoplasmic reticulum-Golgi intermediate compartment and of the Golgi. Belongs to the SURF4 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 9q34.2
Cellular Component: Golgi membrane; endoplasmic reticulum membrane; ER-Golgi intermediate compartment membrane; ER-Golgi intermediate compartment; integral to membrane
Molecular Function: protein binding
Biological Process: protein exit from endoplasmic reticulum; Golgi organization and biogenesis
Research Articles on SURF4
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Product Notes
The SURF4 surf4 (Catalog #AAA9210254) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 211-237. The SURF4 Antibody (C-term) Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) reacts with Mouse (Predicted Reactivity: Bovine) and may cross-react with other species as described in the data sheet. AAA Biotech's SURF4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the SURF4 surf4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SURF4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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