Western Blot (WB)
(Western blot analysis of NRIP1 expression in A498 (Human Kidney Carcinoma) Whole Cell Lysate)
Rabbit anti-Human NRIP1 Polyclonal Antibody | anti-NRIP1 antibody
NRIP1 Antibody
Western Blot (WB)
(Western blot analysis of NRIP1 expression in A498 (Human Kidney Carcinoma) Whole Cell Lysate)
Western Blot (WB)
(Western blot analysis of NRIP1 expression in A498 (Human Kidney Carcinoma) Whole Cell Lysate)
NCBI and Uniprot Product Information
NCBI Description
Nuclear receptor interacting protein 1 (NRIP1) is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors. Also known as RIP140, this protein modulates transcriptional activity of the estrogen receptor. [provided by RefSeq, Jul 2008]
Uniprot Description
RIP140: Modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1. Also modulates transcriptional repression by nuclear hormone receptors. Interacts with RARA and RXRB homodimers and RARA/RXRB heterodimers in the presence of ligand. Interacts with HDAC1 and HDAC3 via its N-terminal domain. Interacts with NR2C1 (sumoylated form and via the ligand-binding domain); the interaction results in promoting the repressor activity of NR2C1. Interacts with CTBP1, CTBP2, ESR1, HDAC1, HDAC2, HDAC5, HDAC6, NR2C2, NR3C1, NR3C2, YWHAH, JUN and FOS. Found in a complex with both NR3C1 and YWHAH. Interacts with ZNF366.
Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 21q11.2
Cellular Component: cell junction; nuclear chromatin; nucleolus; nucleoplasm; nucleus
Molecular Function: estrogen receptor binding; glucocorticoid receptor binding; nuclear hormone receptor binding; protein binding; transcription coactivator activity; transcription corepressor activity
Biological Process: circadian regulation of gene expression; circadian rhythm; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter
Research Articles on NRIP1
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Product Notes
The NRIP1 nrip1 (Catalog #AAA9418271) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NRIP1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NRIP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:500-1:2000. Researchers should empirically determine the suitability of the NRIP1 nrip1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NRIP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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