Testing Data
anti-Human, Mouse EDG6 Antibody | anti-EDG6 antibody
EDG6 Antibody
Gene Names
S1PR4; EDG6; LPC1; S1P4; SLP4
Reactivity
Human, Mouse
Applications
Western Blot, Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
EDG6; EDG6 Antibody; Sphingosine 1-phosphate receptor Edg-6; S1P receptor Edg-6; Endothelial differentiation G-protein coupled receptor 6; Sphingosine 1-phosphate receptor 4; S1P4; anti-EDG6 antibody
Reactivity
Human, Mouse
Specificity
EDG6 antibody detects endogenous levels of total EDG6 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
384
Applicable Applications for anti-EDG6 antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:20000
IF: 1:100~1:500
ELISA: 1:20000
Immunogen
The antiserum was produced against synthesized peptide derived from C-terminal of human EDG6.
Preparation and Storage
Store at-20 degree C for 1 year.
Testing Data
Testing Data
Western Blot (WB)
(Peptide-+ Western blot analysis of extracts from K562 cells, using EDG6 antibody. Immunofluorescence analysis of HepG2 cells, using EDG6 antibody.)
Western Blot (WB)
(Peptide-+ Western blot analysis of extracts from K562 cells, using EDG6 antibody. Immunofluorescence analysis of HepG2 cells, using EDG6 antibody.)
Product Categories/Family for anti-EDG6 antibody
References
Graeler M.H., Genomics 53:164-169(1998). Yamazaki Y., Biochem. Biophys. Res. Commun. 268:583-589(2000). Van Brocklyn J.R., Blood 95:2624-2629(2000).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
41,623 Da
NCBI Official Full Name
sphingosine 1-phosphate receptor 4
NCBI Official Synonym Full Names
sphingosine-1-phosphate receptor 4
NCBI Official Symbol
S1PR4
NCBI Official Synonym Symbols
EDG6; LPC1; S1P4; SLP4
NCBI Protein Information
sphingosine 1-phosphate receptor 4
UniProt Protein Name
Sphingosine 1-phosphate receptor 4
UniProt Gene Name
S1PR4
UniProt Synonym Gene Names
EDG6; S1P receptor 4; S1P4; S1P receptor Edg-6
NCBI Description
This gene is a member of the endothelial differentiation, G-protein-coupled (EDG)) receptor gene family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue. [provided by RefSeq, Jul 2008]
Uniprot Description
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes.
Research Articles on EDG6
1. High S1PR4 expression is associated with anti-neutrophil cytoplasmic antibody-associated vasculitis.
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Product Notes
The EDG6 s1pr4 (Catalog #AAA851208) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The EDG6 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's EDG6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF), ELISA (EIA). WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:20000. Researchers should empirically determine the suitability of the EDG6 s1pr4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EDG6, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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