Rabbit anti-Human, Mouse NPAS3 Polyclonal Antibody | anti-NPAS3 antibody

NPAS3 Rabbit Polyclonal

Cat. Num. AAA7602043

• Gene Names: NPAS3; MOP6; PASD6; bHLHe12
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: NPAS3; Polyclonal Antibody; NPAS3 Rabbit Polyclonal; anti-NPAS3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 933

• Applicable Applications for anti-NPAS3 antibody: ELISA (EIA), Western Blot (WB)
• Immunogen: Neuronal PAS domain protein 3
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Western Blot (WB)

(human brain tissue were subjected to SDS PAGE followed by western blot with MBS7602043 (NPAS3 antibody) at dilution of 1:600)

NCBI and Uniprot Product Information

• NCBI GI #: 260064034
• NCBI GeneID: 64067
• NCBI Accession #: NP_001158221.1
• NCBI GenBank Nucleotide #: NM_001164749.1
• Molecular Weight: 28,563 Da
• NCBI Official Full Name: neuronal PAS domain-containing protein 3 isoform 1
• NCBI Official Synonym Full Names: neuronal PAS domain protein 3
• NCBI Official Symbol: NPAS3
• NCBI Official Synonym Symbols: MOP6; PASD6; bHLHe12
• NCBI Protein Information: neuronal PAS domain-containing protein 3
• UniProt Protein Name: Neuronal PAS domain-containing protein 3
• Protein Family: Neuronal PAS domain-containing protein
• UniProt Gene Name: NPAS3
• UniProt Synonym Gene Names: BHLHE12; MOP6; PASD6; Neuronal PAS3; bHLHe12
• UniProt Entry Name: NPAS3_HUMAN

NCBI Description

This gene encodes a member of the basic helix-loop-helix and PAS domain-containing family of transcription factors. The encoded protein is localized to the nucleus and may regulate genes involved in neurogenesis. Chromosomal abnormalities that affect the coding potential of this gene are associated with schizophrenia and mental retardation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

Uniprot Description

NPAS3: May play a broad role in neurogenesis. May control regulatory pathways relevant to schizophrenia and to psychotic illness. A chromosomal aberration involving NPAS3 is found in a family with schizophrenia. Translocation t(9;14)(q34;q13). 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 14q13.1

Cellular Component: cytoplasm; nucleoplasm

Molecular Function: DNA binding; protein dimerization activity

Biological Process: developmental process; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent