Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Rat Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 Polyclonal Antibody | anti-NOX1 antibody
Polyclonal Antibody to Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1)
Immunohistochemistry: 5-20ug/mL;1:50-200
Immunocytochemistry: 5-20ug/mL;1:50-200
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Small intestine Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Small intestine Tissue))
NCBI and Uniprot Product Information
NCBI Description
involved in superoxide generation and serum-stimulated growth [RGD, Feb 2006]
Uniprot Description
NOX1: NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Channel, misc.; EC 1.-.-.-; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis; Oxidoreductase
Chromosomal Location of Human Ortholog: Xq32
Cellular Component: cell junction; cytoplasm; early endosome; endosome; NADPH oxidase complex
Molecular Function: metal ion binding; protein binding; Rac GTPase binding; superoxide-generating NADPH oxidase activity; voltage-gated proton channel activity
Biological Process: angiogenesis; cell migration; extracellular matrix organization; hydrogen peroxide metabolic process; intracellular pH elevation; positive regulation of cell proliferation; positive regulation of integrin biosynthetic process; positive regulation of JNK cascade; positive regulation of MAPK cascade; positive regulation of smooth muscle cell proliferation; proton transport; regulation of systemic arterial blood pressure by renin-angiotensin; response to reactive oxygen species; signal transduction; superoxide anion generation; superoxide metabolic process
Research Articles on NOX1
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Product Notes
The NOX1 nox1 (Catalog #AAA2028234) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.5-2ug/mL;1:500-2000 Immunohistochemistry: 5-20ug/mL;1:50-200 Immunocytochemistry: 5-20ug/mL;1:50-200 Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the NOX1 nox1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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