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Western Blot (WB) (All lanes: N-alpha-acetyltransferase 10 antibody at 5ug/ml+Hela whole cell lysate)

Rabbit anti-Human NAA10 Polyclonal Antibody | anti-NAA10 antibody

NAA10 Polyclonal Antibody

Gene Names
NAA10; TE2; ARD1; NATD; ARD1A; ARD1P; OGDNS; DXS707; MCOPS1
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
NAA10; Polyclonal Antibody; NAA10 Polyclonal Antibody; N-alpha-acetyltransferase 10; N-terminal acetyltransferase complex ARD1 subunit homolog A; NatA catalytic subunit Naa10; ARD1; ARD1A; TE2; anti-NAA10 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total NAA10 polyclonal antibody.
Purity/Purification
Antigen Affinity Purified
Form/Format
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
220
Applicable Applications for anti-NAA10 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western Blot: 1:500 - 1:5000
Immunohistochemistry: 1:20 - 1:200
Immunogen
Recombinant Human N-alpha-acetyltransferase 10 protein(161-235aa)
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(All lanes: N-alpha-acetyltransferase 10 antibody at 5ug/ml+Hela whole cell lysate)

Western Blot (WB) (All lanes: N-alpha-acetyltransferase 10 antibody at 5ug/ml+Hela whole cell lysate)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human rectal cancer using at dilution of 1:100.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human rectal cancer using at dilution of 1:100.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human testicle using at dilution of 1:100.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human testicle using at dilution of 1:100.)
Related Product Information for anti-NAA10 antibody
Catalytic subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity. The NAT activity may be important for vascular, hematopoietic and neuronal growth and development.Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration. Acetylates, and stabilizes TSC2, thereby repressing mTOR activity and suppressing cancer development.
Product Categories/Family for anti-NAA10 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
24,784 Da
NCBI Official Full Name
N-alpha-acetyltransferase 10 isoform 2
NCBI Official Synonym Full Names
N(alpha)-acetyltransferase 10, NatA catalytic subunit
NCBI Official Symbol
NAA10
NCBI Official Synonym Symbols
TE2; ARD1; NATD; ARD1A; ARD1P; OGDNS; DXS707; MCOPS1
NCBI Protein Information
N-alpha-acetyltransferase 10
UniProt Protein Name
N-alpha-acetyltransferase 10
Protein Family
UniProt Gene Name
NAA10
UniProt Synonym Gene Names
ARD1; ARD1A; TE2
UniProt Entry Name
NAA10_HUMAN

Uniprot Description

NAA10: In complex with NAA15, displays alpha (N-terminal) acetyltransferase activity. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration. Interacts with HIF1A (via its ODD domain); the interaction increases HIF1A protein stability during normoxia, and down-regulates it when induced by hypoxia. Interacts with NAA15, NAA50 and with the ribosome. Binds to MYLK. Ubiquitous. Belongs to the acetyltransferase family. ARD1 subfamily.

Protein type: Acetyltransferase; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - tyrosine; EC 2.3.1.88; Lipid Metabolism - glycerophospholipid; Secondary Metabolites Metabolism - limonene and pinene degradation

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: cytoplasm; intracellular; membrane; nucleolus; nucleus

Molecular Function: acetyltransferase activity; N-acetyltransferase activity; peptide alpha-N-acetyltransferase activity; protein binding; ribosome binding

Biological Process: DNA packaging; internal protein amino acid acetylation; N-terminal peptidyl-glutamic acid acetylation; N-terminal peptidyl-serine acetylation; N-terminal protein amino acid acetylation

Disease: Microphthalmia, Syndromic 1; Ogden Syndrome

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Product Notes

The NAA10 naa10 (Catalog #AAA9416253) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NAA10 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NAA10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: 1:500 - 1:5000 Immunohistochemistry: 1:20 - 1:200. Researchers should empirically determine the suitability of the NAA10 naa10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NAA10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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