Western Blot (WB)
(Western Blot analysis in human placenta tissue lysates (35ug/lane) usingMBS649002. This demonstrates that MBS649002 detected the MUL1 protein (arrow).)
Rabbit anti-Human MUL1 Polyclonal Antibody | anti-MUL1 antibody
MUL1, CT (MUL1, C1orf166, GIDE, MAPL, MULAN, RNF218, Mitochondrial ubiquitin ligase activator of NFKB 1, E3 SUMO-protein ligase MUL1, E3 ubiquitin-protein ligase MUL1, Growth inhibition and death E3 ligase, Mitochondrial-anchored protein ligase, Putative
Gene Names
MUL1; GIDE; MAPL; MULAN; RNF218; C1orf166; RP11-401M16.2
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Protein A and Peptide Affinity Chromatography.
Synonyms
MUL1; Polyclonal Antibody; CT (MUL1; C1orf166; GIDE; MAPL; MULAN; RNF218; Mitochondrial ubiquitin ligase activator of NFKB 1; E3 SUMO-protein ligase MUL1; E3 ubiquitin-protein ligase MUL1; Growth inhibition and death E3 ligase; Mitochondrial-anchored protein ligase; Putative; mitochondrial ubiquitin ligase activator of NFKB 1; mitochondrial-anchored protein ligase; Putative NF-kappa-B-activating protein 266; RING finger protein 218; anti-MUL1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human MUL1.
Purity/Purification
Purified by Protein A and Peptide Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-MUL1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 272-301 in the C-terminal region of human MUL1, UniProt Accession #Q969V5. Species sequence homology: monkey
Conjugate
Biotin
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot analysis in human placenta tissue lysates (35ug/lane) usingMBS649002. This demonstrates that MBS649002 detected the MUL1 protein (arrow).)
Western Blot (WB)
(Western Blot analysis in human placenta tissue lysates (35ug/lane) usingMBS649002. This demonstrates that MBS649002 detected the MUL1 protein (arrow).)
Related Product Information for anti-MUL1 antibody
E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Product Categories/Family for anti-MUL1 antibody
References
1. Laure, L., et al. FEBS J. 277(20):4322-4337(2010). 2. Braschi, E., et al. EMBO Rep. 10(7):748-754(2009). 3. Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009). 4. Zhang, B., et al. Cell Res. 18(9):900-910(2008). 5. Zhang, H., et al. Biochem. Biophys. Res. Commun. 366(4):898-904(2008).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39,800 Da
NCBI Official Full Name
mitochondrial ubiquitin ligase activator of NFKB 1
NCBI Official Synonym Full Names
mitochondrial E3 ubiquitin protein ligase 1
NCBI Official Symbol
MUL1
NCBI Official Synonym Symbols
GIDE; MAPL; MULAN; RNF218; C1orf166; RP11-401M16.2
NCBI Protein Information
mitochondrial ubiquitin ligase activator of NFKB 1; E3 ubiquitin ligase; ring finger protein 218; E3 SUMO-protein ligase MUL1; E3 ubiquitin-protein ligase MUL1; mitochondrial E3 ubiquitin ligase 1; mitochondria-anchored protein ligase; growth inhibition a
UniProt Protein Name
Mitochondrial ubiquitin ligase activator of NFKB 1
Protein Family
UniProt Gene Name
MUL1
UniProt Synonym Gene Names
C1orf166; GIDE; MAPL; MULAN; RNF218; MAPL
UniProt Entry Name
MUL1_HUMAN
Research Articles on MUL1
1. MULAN negatively regulates Akt signaling, facilitating the control of multiple cellular processes.
Similar Products
Product Notes
The MUL1 mul1 (Catalog #AAA6322980) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MUL1, CT (MUL1, C1orf166, GIDE, MAPL, MULAN, RNF218, Mitochondrial ubiquitin ligase activator of NFKB 1, E3 SUMO-protein ligase MUL1, E3 ubiquitin-protein ligase MUL1, Growth inhibition and death E3 ligase, Mitochondrial-anchored protein ligase, Putative reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MUL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the MUL1 mul1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MUL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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