Rabbit anti-Human MUL1 Polyclonal Antibody | anti-MUL1 antibody

MUL1, CT (MUL1, C1orf166, GIDE, MAPL, MULAN, RNF218, Mitochondrial ubiquitin ligase activator of NFKB 1, E3 SUMO-protein ligase MUL1, E3 ubiquitin-protein ligase MUL1, Growth inhibition and death E3 ligase, Mitochondrial-anchored protein ligase, Putative

Cat. Num. AAA6322986

• Gene Names: MUL1; GIDE; MAPL; MULAN; RNF218; C1orf166; RP11-401M16.2
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A and Peptide Affinity Chromatography.
• Synonyms: MUL1; Polyclonal Antibody; CT (MUL1; C1orf166; GIDE; MAPL; MULAN; RNF218; Mitochondrial ubiquitin ligase activator of NFKB 1; E3 SUMO-protein ligase MUL1; E3 ubiquitin-protein ligase MUL1; Growth inhibition and death E3 ligase; Mitochondrial-anchored protein ligase; Putative; mitochondrial ubiquitin ligase activator of NFKB 1; mitochondrial-anchored protein ligase; Putative NF-kappa-B-activating protein 266; RING finger protein 218; anti-MUL1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human MUL1.
• Purity/Purification: Purified by Protein A and Peptide Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.

• Applicable Applications for anti-MUL1 antibody: Western Blot (WB), FLISA
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 272-301 in the C-terminal region of human MUL1, UniProt Accession #Q969V5. Species sequence homology: monkey
• Conjugate: MaxLight650
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot analysis in human placenta tissue lysates (35ug/lane) usingMBS649002. This demonstrates that MBS649002 detected the MUL1 protein (arrow).)

Related Product Information for anti-MUL1 antibody

E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Product Categories/Family for anti-MUL1 antibody

Antibodies; Ubiquitin Ligases

References

1. Laure, L., et al. FEBS J. 277(20):4322-4337(2010). 2. Braschi, E., et al. EMBO Rep. 10(7):748-754(2009). 3. Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009). 4. Zhang, B., et al. Cell Res. 18(9):900-910(2008). 5. Zhang, H., et al. Biochem. Biophys. Res. Commun. 366(4):898-904(2008).

NCBI and Uniprot Product Information

• NCBI GI #: 171542821
• NCBI GeneID: 79594
• NCBI Accession #: NP_078820.2
• NCBI GenBank Nucleotide #: NM_024544.2
• UniProt Accession #: Q969V5; Q7Z431; Q9H9B5; B5M497
• Molecular Weight: 39,800 Da
• NCBI Official Full Name: mitochondrial ubiquitin ligase activator of NFKB 1
• NCBI Official Synonym Full Names: mitochondrial E3 ubiquitin protein ligase 1
• NCBI Official Symbol: MUL1
• NCBI Official Synonym Symbols: GIDE; MAPL; MULAN; RNF218; C1orf166; RP11-401M16.2
• NCBI Protein Information: mitochondrial ubiquitin ligase activator of NFKB 1; E3 ubiquitin ligase; ring finger protein 218; E3 SUMO-protein ligase MUL1; E3 ubiquitin-protein ligase MUL1; mitochondrial E3 ubiquitin ligase 1; mitochondria-anchored protein ligase; growth inhibition a
• UniProt Protein Name: Mitochondrial ubiquitin ligase activator of NFKB 1
• Protein Family: Mitochondrial ubiquitin ligase activator
• UniProt Gene Name: MUL1
• UniProt Synonym Gene Names: C1orf166; GIDE; MAPL; MULAN; RNF218; MAPL
• UniProt Entry Name: MUL1_HUMAN