Rabbit MIER1 Polyclonal Antibody | anti-MIER1 antibody

MIER1 Rabbit Polyclonal

Cat. Num. AAA7601417

• Gene Names: MIER1; ER1; MI-ER1
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: MIER1; Polyclonal Antibody; MIER1 Rabbit Polyclonal; anti-MIER1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 81

• Applicable Applications for anti-MIER1 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Immunogen: Mesoderm induction early response 1 homolog (Xenopus laevis)
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human pancreas cancer tissue slide using MBS7601417 (MIER1 Antibody) at dilution of 1:50)

Western Blot (WB)

(human testis tissue were subjected to SDS PAGE followed by western blot with MBS7601417 (MIER1 antibody) at dilution of 1:500)

NCBI and Uniprot Product Information

• NCBI GI #: 501354918
• NCBI GeneID: 57708
• NCBI Accession #: NP_001265144.1
• NCBI GenBank Nucleotide #: NM_001278215.1
• Molecular Weight: 9,357 Da
• NCBI Official Full Name: mesoderm induction early response protein 1 isoform j
• NCBI Official Synonym Full Names: MIER1 transcriptional regulator
• NCBI Official Symbol: MIER1
• NCBI Official Synonym Symbols: ER1; MI-ER1
• NCBI Protein Information: mesoderm induction early response protein 1
• UniProt Protein Name: Mesoderm induction early response protein 1
• Protein Family: Mesoderm induction early response protein
• UniProt Gene Name: MIER1
• UniProt Synonym Gene Names: KIAA1610; Early response 1; Er1; Mi-er1; hMi-er1
• UniProt Entry Name: MIER1_HUMAN

NCBI Description

This gene encodes a protein that was first identified in Xenopus laevis by its role in a mesoderm induction early response (MIER). The encoded protein functions as a transcriptional regulator. Alternatively spliced transcript variants encode multiple isoforms, some of which lack a C-terminal nuclear localization signal. [provided by RefSeq, May 2013]

Uniprot Description

MIER1: a transcriptional repressor which acts through recruitment of HDAC1. Contains a Myb-like DNA-binding and ELM2 domain. Its expression is associated with breast carcinoma

Protein type: Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 1p31.3

Cellular Component: cytoplasm; nucleoplasm; transcriptional repressor complex

Molecular Function: DNA binding; protein binding; signal transducer activity

Biological Process: positive regulation of chromatin silencing; positive regulation of I-kappaB kinase/NF-kappaB cascade; signal transduction; transcription, DNA-dependent