Rabbit anti-Human MIER1 Polyclonal Antibody | anti-MIER1 antibody

MIER1, ID (MIER1, KIAA1610, Mesoderm induction early response protein 1) (Biotin)

Cat. Num. AAA6320791

• Gene Names: MIER1; ER1; MI-ER1
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: MIER1; Polyclonal Antibody; ID (MIER1; KIAA1610; Mesoderm induction early response protein 1) (Biotin); Mesoderm induction early response protein 1; anti-MIER1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
• Sequence Length: 512

• Applicable Applications for anti-MIER1 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: MIER1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 238-266 amino acids from the Central region of human MIER1.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(MIER1 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the MIER1 antibody detected the MIER1 protein (arrow).)

Related Product Information for anti-MIER1 antibody

Transcriptional repressor of a number of genes including Sp1 target genes.

Product Categories/Family for anti-MIER1 antibody

Antibodies; KIAA; orf

References

McCarthy, P.L., et al. Br. J. Cancer 99(4):639-646(2008). Olsen, J.V., et al. Cell 127(3):635-648(2006). Olsen, J.V., et al. Cell 127(3):635-648(2006). Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006). Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 118130815
• NCBI GeneID: 57708
• NCBI Accession #: NP_001071169.1
• NCBI GenBank Nucleotide #: NP_001071169.1
• UniProt Accession #: Q8N108
• NCBI Official Full Name: mesoderm induction early response protein 1 isoform c
• NCBI Official Synonym Full Names: MIER1 transcriptional regulator
• NCBI Official Symbol: MIER1
• NCBI Official Synonym Symbols: ER1; MI-ER1
• NCBI Protein Information: mesoderm induction early response protein 1
• UniProt Protein Name: Mesoderm induction early response protein 1
• Protein Family: Mesoderm induction early response protein
• UniProt Gene Name: MIER1
• UniProt Synonym Gene Names: KIAA1610; Early response 1; Er1; Mi-er1; hMi-er1
• UniProt Entry Name: MIER1_HUMAN

NCBI Description

This gene encodes a protein that was first identified in Xenopus laevis by its role in a mesoderm induction early response (MIER). The encoded protein functions as a transcriptional regulator. Alternatively spliced transcript variants encode multiple isoforms, some of which lack a C-terminal nuclear localization signal. [provided by RefSeq, May 2013]