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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using METTL1 Polyclonal Antibody at dilution of 1:50(×200))

Rabbit anti-Human, Mouse METTL1 Polyclonal Antibody | anti-METTL1 antibody

METTL1 Polyclonal Antibody

Gene Names
METTL1; TRM8; TRMT8; C12orf1; YDL201w
Reactivity
Human, Mouse
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
METTL1; Polyclonal Antibody; METTL1 Polyclonal Antibody; C12orf1; D1075 like gene product; FLJ95748; Methyltransferase like 1; Methyltransferase like protein 1; Methyltransferase-like protein 1; Mettl1; TRM8; TRMB_HUMAN; TRMT8; TRNA (guanine N(7)) methyltransferase; TRNA (guanine(46)-N(7))-methyltransferase; TRNA (guanine-N(7)-)-methyltransferase; TRNA(m7G46) methyltransferase; TRNA(m7G46)-methyltransferase; YDL201w; anti-METTL1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
0.6mg/mL (varies by lot)
Sequence Length
276
Applicable Applications for anti-METTL1 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:50-1:300
ELISA: 1:5000-1:10000
Immunogen
Fusion protein of human METTL1
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using METTL1 Polyclonal Antibody at dilution of 1:50(×200))

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using METTL1 Polyclonal Antibody at dilution of 1:50(×200))

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using METTL1 Polyclonal Antibody at dilution of 1:50(×200))

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using METTL1 Polyclonal Antibody at dilution of 1:50(×200))
Related Product Information for anti-METTL1 antibody
This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X.
Product Categories/Family for anti-METTL1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
tRNA (guanine-N(7)-)-methyltransferase isoform a
NCBI Official Synonym Full Names
methyltransferase like 1
NCBI Official Symbol
METTL1
NCBI Official Synonym Symbols
TRM8; TRMT8; C12orf1; YDL201w
NCBI Protein Information
tRNA (guanine-N(7)-)-methyltransferase
UniProt Protein Name
tRNA (guanine-N(7)-)-methyltransferase
UniProt Gene Name
METTL1
UniProt Entry Name
TRMB_HUMAN

NCBI Description

This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X. [provided by RefSeq, Jul 2008]

Uniprot Description

METTL1: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. Belongs to the methyltransferase superfamily. TrmB family.

Protein type: Methyltransferase; EC 2.1.1.33; RNA processing

Chromosomal Location of Human Ortholog: 12q13

Cellular Component: nucleoplasm; cytoplasm; nucleolus; nucleus

Molecular Function: protein binding; tRNA (guanine-N7-)-methyltransferase activity; tRNA binding

Biological Process: tRNA modification; tRNA methylation

Research Articles on METTL1

Similar Products

Product Notes

The METTL1 mettl1 (Catalog #AAA2560849) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The METTL1 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's METTL1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:50-1:300 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the METTL1 mettl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "METTL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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