Rabbit Matrix Metalloproteinase 2 Polyclonal Antibody | anti-MMP-2 antibody
Matrix Metalloproteinase 2 (MMP-2, Collagenase IV, Gelatinase A) (BSA & Azide Free)
Reactivity
Human, Mouse, Rat, Bovine
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
Matrix Metalloproteinase 2; Polyclonal Antibody; Matrix Metalloproteinase 2 (MMP-2; Collagenase IV; Gelatinase A) (BSA & Azide Free); anti-MMP-2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat, Bovine
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human Matrix Metalloproteinase 2 (MMP-2, Collagenase IV, Gelatinase A). Species Crossreactivity: mouse, rat and bovine.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.
Applicable Applications for anti-MMP-2 antibody
Western Blot (WB)
Application Notes
WB: 5-10ug/ml for 2 hrs at RT.
Applications are based on unconjugated antibody.
Applications are based on unconjugated antibody.
Immunogen
A synthetic peptide from the second half of human MMP-2. Cellular Localization: Cytoplasmic. MW of Antigen: 7~2kD (pro form) and ~66kD (active form).
Conjugate
MaxLight750
Positive Control
Conditioned, serum-free medium from (TPA-treated) HFl-1 cells.
Note
Preservative Free
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-MMP-2 antibody
MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPs and TIMPs play a significant role in regulating angiogenesis. MMP-2; also known as 72kD collagenase IV or gelatinase A is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids.
Product Categories/Family for anti-MMP-2 antibody
References
1. Margulies IM, et. al. Cancer Epidemiology, Biomarkers and Prevention, 1992, 1(6):467-74. 2. Soini Y, et. al. J Histochem Cytochem, 1994, 42:945-51. 3. Autio-Harmainen H, et al. Lab Invest, 1993, 69:312-321. 4. Autio-Harmainen H, et al. Lab Invest, 1992, 67:191-200. 5. Nikkari S T, et al. Am J PAthol, 1996, 149:1427-1433. 6. Fridman R, et al. J Biol Chem, 1992, 267:15398-15405. 7. Schnaper H W, et al. J Cell Physiol, 1993, 156:235-246.
Similar Products
Product Notes
The MMP-2 (Catalog #AAA6486978) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Matrix Metalloproteinase 2 (MMP-2, Collagenase IV, Gelatinase A) (BSA & Azide Free) reacts with Human, Mouse, Rat, Bovine and may cross-react with other species as described in the data sheet. AAA Biotech's Matrix Metalloproteinase 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 5-10ug/ml for 2 hrs at RT. Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the MMP-2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Matrix Metalloproteinase 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
