Rabbit MAP Kinase p44/42 Polyclonal Antibody | anti-MAPK1 antibody
MAP Kinase p44/42 (MAPK3/MAPK1, Mitogen-activated Protein Kinase 1, MAP Kinase 1, MAPK 1, ERT1, Extracellular Signal-regulated Kinase 2, ERK-2, MAP Kinase Isoform p42, p42-MAPK, Mitogen-activated Protein Kinase 2, MAP Kinase 2, MAPK 2, ERK2, PRKM1, PRKM2
Reactivity
Bovine, Chicken, Drosophila, Human, Mouse, Rat, Sheep, Xenopus
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry
Purity
SerumSerum
Synonyms
MAP Kinase p44/42; Polyclonal Antibody; MAP Kinase p44/42 (MAPK3/MAPK1; Mitogen-activated Protein Kinase 1; MAP Kinase 1; MAPK 1; ERT1; Extracellular Signal-regulated Kinase 2; ERK-2; MAP Kinase Isoform p42; p42-MAPK; Mitogen-activated Protein Kinase 2; MAP Kinase 2; MAPK 2; ERK2; PRKM1; PRKM2; Anti -MAP Kinase p44/42 (MAPK3/MAPK1; anti-MAPK1 antibody
Host
Rabbit
Reactivity
Bovine, Chicken, Drosophila, Human, Mouse, Rat, Sheep, Xenopus
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes ERK 1/2. Species Crossreactivity: human, mouse, rat, bovine, sheep, chicken, drosophila, xenopus.
Purity/Purification
Serum
Serum
Serum
Form/Format
Supplied as a liquid.
Applicable Applications for anti-MAPK1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
Application Notes
Suitable for use in Flow Cytometry, Western Blot, Immunohistochemistry and Immunocytochemistry.
Dilution: Flow Cytometry: 10ug/ml
Western Blot: 1:5000
Immunohistochemistry:1:50
Dilution: Flow Cytometry: 10ug/ml
Western Blot: 1:5000
Immunohistochemistry:1:50
Immunogen
A 35 residue synthetic peptide, corresponding to Erk1 MAP kinase with the CGG spacer group added and the peptide coupled to KLH.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-MAPK1 antibody
The extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2), also called p44 and p42 MAP kinases, are members of the Mitogen Activated Protein Kinase (MAPK) family of proteins found in all eukaryotes. Because the 44kD ERK1 and the 42kD ERK2 are highly homologous and both function in the same protein kinase cascade, the two proteins are often referred to collectively as ERK1/2 or p44/p42 MAP kinase (1). They are both located in the cytosol and mitochondria (2). While the role of cytosol ERK1/2 is well studied and involved in multiple cellular functions (2), the role of mitochondrial ERK1/2 remains poorly understood. Both ERK 1 and 2 are activated by MEK1 or MEK2, by dual phosphorylation of a threonine and tyrosine residue in the activation loop (TEY motif) (1, 3). Either phosphorylation alone can induce an electrophoretic mobility shift, but both are required for activation of the kinase. This dual phosphorylation is efficiently detected by phosphorylation state-specific antibody directed to
Product Categories/Family for anti-MAPK1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
mitogen-activated protein kinase 1
NCBI Official Synonym Full Names
mitogen-activated protein kinase 1
NCBI Official Symbol
MAPK1
NCBI Protein Information
mitogen-activated protein kinase 1
Research Articles on MAPK1
Similar Products
Product Notes
The MAPK1 (Catalog #AAA621454) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MAP Kinase p44/42 (MAPK3/MAPK1, Mitogen-activated Protein Kinase 1, MAP Kinase 1, MAPK 1, ERT1, Extracellular Signal-regulated Kinase 2, ERK-2, MAP Kinase Isoform p42, p42-MAPK, Mitogen-activated Protein Kinase 2, MAP Kinase 2, MAPK 2, ERK2, PRKM1, PRKM2 reacts with Bovine, Chicken, Drosophila, Human, Mouse, Rat, Sheep, Xenopus and may cross-react with other species as described in the data sheet. AAA Biotech's MAP Kinase p44/42 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC). Suitable for use in Flow Cytometry, Western Blot, Immunohistochemistry and Immunocytochemistry. Dilution: Flow Cytometry: 10ug/ml Western Blot: 1:5000 Immunohistochemistry:1:50. Researchers should empirically determine the suitability of the MAPK1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAP Kinase p44/42, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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