Western Blot (WB)
(Anti-LRRC3B rabbit polyclonal antibody at 1:500 dilutionLane A: A549 Whole Cell LysateLane B: HEK293 Whole Cell LysateLysates/proteins at 30 ug per lane.SecondaryGoat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.Developed using the Odyssey technique. Performed under reducing conditions.Predicted band size:29 kDaObserved band size:38 kDa)
Rabbit anti-Human LRRC3B Polyclonal Antibody | anti-LRRC3B antibody
Anti-LRRC3B Antibody, Rabbit Polyclonal
Gene Names
LRRC3B; LRP15
Reactivity
Human
Applications
Western Blot
Purity
Protein A & Antigen Affinity
Synonyms
LRRC3B; Polyclonal Antibody; Anti-LRRC3B Antibody; Rabbit Polyclonal; LRRC3B Antibody; Rabbit PAb; Antigen Affinity Purified; leucine rich repeat containing 3B; Anti-LRP15 Antibody; anti-LRRC3B antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human LRRC3B
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-LRRC3B antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant Human LRRC3B Protein
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with purified, recombinant Human LRRC3B (rh LRRC3B). LRRC3B specific IgG was purified by Human LRRC3B affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Western Blot (WB)
(Anti-LRRC3B rabbit polyclonal antibody at 1:500 dilutionLane A: A549 Whole Cell LysateLane B: HEK293 Whole Cell LysateLysates/proteins at 30 ug per lane.SecondaryGoat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.Developed using the Odyssey technique. Performed under reducing conditions.Predicted band size:29 kDaObserved band size:38 kDa)
Western Blot (WB)
(Anti-LRRC3B rabbit polyclonal antibody at 1:500 dilutionLane A: A549 Whole Cell LysateLane B: HEK293 Whole Cell LysateLysates/proteins at 30 ug per lane.SecondaryGoat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.Developed using the Odyssey technique. Performed under reducing conditions.Predicted band size:29 kDaObserved band size:38 kDa)
Related Product Information for anti-LRRC3B antibody
LRRC3B expression is downregulated in many kinds of malignant tumors and it is regarded as a tumor inhibition protein. The leucine-rich repeat-containing 3B (LRRC3B) gene is a putative tumor suppressor located on human chromosome 3 in the 3p24 region. LRRC3B is frequently altered in colon and gastric cancers and also in leukemias.LRRC3B expression is downregulated in lung cancer cell lines and LRRC3B could inhibit lung cancer cell proliferation, invasion, and cell cycle progress. LRRC3B could be a new target for lung cancer therapy.LRRC3B depletion in HBE cells promoted proliferation and invasion, suggesting that LRRC3B may serve as an important tumor suppressor in NSCLC.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
29,275 Da
NCBI Official Full Name
leucine-rich repeat-containing protein 3B
NCBI Official Synonym Full Names
leucine rich repeat containing 3B
NCBI Official Symbol
LRRC3B
NCBI Official Synonym Symbols
LRP15
NCBI Protein Information
leucine-rich repeat-containing protein 3B; leucine-rich repeat protein LRP15
UniProt Protein Name
Leucine-rich repeat-containing protein 3B
Protein Family
UniProt Gene Name
LRRC3B
UniProt Synonym Gene Names
LRP15
UniProt Entry Name
LRC3B_HUMAN
Uniprot Description
LRRC3B: Belongs to the LRRC3 family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 3p24
Cellular Component: integral to membrane
Research Articles on LRRC3B
Similar Products
Product Notes
The LRRC3B lrrc3b (Catalog #AAA8107526) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-LRRC3B Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LRRC3B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the LRRC3B lrrc3b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LRRC3B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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