SDS-Page
LRRC3B recombinant protein
LRRC3B Protein, Human, Recombinant (hFc Tag)
Gene Names
LRRC3B; LRP15
Purity
>95% as determined by SDS-PAGE
Synonyms
LRRC3B; LRRC3B Protein; Human; Recombinant (hFc Tag); Human LRRC3B/LRP15 Protein (Fc Tag); LRP15 Protein; leucine rich repeat containing 3B; LRRC3B recombinant protein
Host
HEK293 Cells
Purity/Purification
>95% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Sequence
Met1-Tyr204
Species
Human
Endotoxin
<1.0EU per ug protein as determined by the LAL method.
Predicted N Terminal
Cys 34
Tag
C-human IgG1-Fc
Protein Construction
A DNA sequence encoding the human LRRC3B (NP_443185.1)(Met1-Tyr204) was expressed with the Fc region of human IgG1 at the C-terminus.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
SDS-Page
SDS-Page
Related Product Information for LRRC3B recombinant protein
Background: LRRC3B expression is downregulated in many kinds of malignant tumors and it is regarded as a tumor inhibition protein. The leucine-rich repeat-containing 3B (LRRC3B) gene is a putative tumor suppressor located on human chromosome 3 in the 3p24 region. LRRC3B is frequently altered in colon and gastric cancers and also in leukemias.LRRC3B expression is downregulated in lung cancer cell lines and LRRC3B could inhibit lung cancer cell proliferation, invasion, and cell cycle progress. LRRC3B could be a new target for lung cancer therapy.LRRC3B depletion in HBE cells promoted proliferation and invasion, suggesting that LRRC3B may serve as an important tumor suppressor in NSCLC.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
29,275 Da
NCBI Official Full Name
leucine-rich repeat-containing protein 3B
NCBI Official Synonym Full Names
leucine rich repeat containing 3B
NCBI Official Symbol
LRRC3B
NCBI Official Synonym Symbols
LRP15
NCBI Protein Information
leucine-rich repeat-containing protein 3B; leucine-rich repeat protein LRP15
UniProt Protein Name
Leucine-rich repeat-containing protein 3B
Protein Family
UniProt Gene Name
LRRC3B
UniProt Synonym Gene Names
LRP15
UniProt Entry Name
LRC3B_HUMAN
Uniprot Description
LRRC3B: Belongs to the LRRC3 family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 3p24
Cellular Component: integral to membrane
Research Articles on LRRC3B
Similar Products
Product Notes
The LRRC3B lrrc3b (Catalog #AAA8121814) is a Recombinant Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Met1-Tyr20 4. It is sometimes possible for the material contained within the vial of "LRRC3B, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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