Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human prostate cancer using MBS7000445 at dilution of 1:100)
Rabbit anti-Human LPXN Polyclonal Antibody | anti-LPXN antibody
LPXN Antibody
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human prostate cancer using MBS7000445 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human prostate cancer using MBS7000445 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human lymph node tissue using MBS7000445 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human lymph node tissue using MBS7000445 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunofluorescent analysis of PC3 cells using MBS7000445 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Immunohistochemistry (IHC)
(Immunofluorescent analysis of PC3 cells using MBS7000445 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Western Blot (WB)
(Western BlotPositive WB detected in: Jurkat whole cell lysateAll lanes: LPXN antibody at 2ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 44 KDaObserved band size: 44 KDa)
Western Blot (WB)
(Western BlotPositive WB detected in: Jurkat whole cell lysateAll lanes: LPXN antibody at 2ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 44 KDaObserved band size: 44 KDa)
NCBI and Uniprot Product Information
NCBI Description
The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]
Uniprot Description
leupaxin: a LIM domain-containing cytoplasmic protein preferentially expressed in hematopoietic cells. Homologous to the focal adhesion protein, paxillin. Associates with PYK2, a member of focal adhesion kinase family, it may participate in signaling at sites of adhesion. .
Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis; Cytoskeletal
Chromosomal Location of Human Ortholog: 11q12.1
Cellular Component: cell projection; cytoplasm; focal adhesion; membrane; nucleus; perinuclear region of cytoplasm; plasma membrane; podosome
Molecular Function: protein binding; transcription cofactor activity; zinc ion binding
Biological Process: cell adhesion; negative regulation of B cell receptor signaling pathway; negative regulation of cell adhesion; protein complex assembly; regulation of cell adhesion mediated by integrin; regulation of transcription, DNA-dependent; signal transduction; transcription, DNA-dependent
Research Articles on LPXN
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Product Notes
The LPXN lpxn (Catalog #AAA7000445) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LPXN Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LPXN can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF). Researchers should empirically determine the suitability of the LPXN lpxn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LPXN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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