Western Blot/Blotting
(Western blot analysis using Pan PPAP antibody on human brain lysate.)
Rabbit Lipid Phosphate Phosphohydrolase 2 Polyclonal Antibody | anti-PPAP2C antibody
Lipid Phosphate Phosphohydrolase 2
Western Blot/Blotting
(Western blot analysis using Pan PPAP antibody on human brain lysate.)
Western Blot/Blotting
(Western blot analysis using Pan PPAP antibody on human brain lysate.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B). All three proteins contain 6 transmembrane regions, and a consensus N-glycosylation site. This protein has been shown to possess membrane associated PAP activity. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Uniprot Description
Function: Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is PA > C-1-P > LPA > S-1-P.
Catalytic activity: A 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate.
Enzyme regulation: Inhibited by sphingosine, zinc ions and propanolol.
Subunit structure: Homodimer
By similarity.
Subcellular location: Membrane; Multi-pass membrane protein.
Tissue specificity: Found mainly in brain, pancreas and placenta.
Sequence similarities: Belongs to the PA-phosphatase related phosphoesterase family.
Research Articles on PPAP2C
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Product Notes
The PPAP2C ppap2c (Catalog #AAA395724) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Lipid Phosphate Phosphohydrolase 2 reacts with Human, Porcine and may cross-react with other species as described in the data sheet. AAA Biotech's Lipid Phosphate Phosphohydrolase 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). Researchers should empirically determine the suitability of the PPAP2C ppap2c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Lipid Phosphate Phosphohydrolase 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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