Western Blot (WB)
(Western blotAll lanes: PPAP2C antibody at 8ug/mlLane 1: A549 whole cell lysateLane 2: MCF7 whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 33,35,27 kDaObserved band size: 33 kDa)
Rabbit anti-Human PPAP2C Polyclonal Antibody | anti-PPAP2C antibody
PPAP2C Antibody
Western Blot (WB)
(Western blotAll lanes: PPAP2C antibody at 8ug/mlLane 1: A549 whole cell lysateLane 2: MCF7 whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 33,35,27 kDaObserved band size: 33 kDa)
Western Blot (WB)
(Western blotAll lanes: PPAP2C antibody at 8ug/mlLane 1: A549 whole cell lysateLane 2: MCF7 whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 33,35,27 kDaObserved band size: 33 kDa)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human colon cancer using MBS7005093 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human colon cancer using MBS7005093 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human small intestine tissue using MBS7005093 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human small intestine tissue using MBS7005093 at dilution of 1:100)
Immunofluorescence (IF)
(Immunofluorescent analysis of A549 cells using MBS7005093 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Immunofluorescence (IF)
(Immunofluorescent analysis of A549 cells using MBS7005093 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B). All three proteins contain 6 transmembrane regions, and a consensus N-glycosylation site. This protein has been shown to possess membrane associated PAP activity. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Uniprot Description
PPAP2C: Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1- phosphate (S-1-P). The relative catalytic efficiency is PA > C-1-P > LPA > S-1-P. Belongs to the PA-phosphatase related phosphoesterase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Lipid Metabolism - glycerophospholipid; Lipid Metabolism - glycerolipid; Membrane protein, integral; Phosphatase, lipid; EC 3.1.3.4; Lipid Metabolism - sphingolipid; Membrane protein, multi-pass; Motility/polarity/chemotaxis; Lipid Metabolism - ether lipid
Chromosomal Location of Human Ortholog: 19p13
Cellular Component: integral to plasma membrane; membrane; plasma membrane
Molecular Function: lipid phosphatase activity; phosphatidate phosphatase activity; phosphoprotein phosphatase activity; protein binding
Biological Process: phospholipid dephosphorylation; phospholipid metabolic process; protein amino acid dephosphorylation; signal transduction; sphingolipid biosynthetic process; sphingolipid metabolic process
Research Articles on PPAP2C
Similar Products
Product Notes
The PPAP2C plpp2 (Catalog #AAA7005093) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PPAP2C Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PPAP2C can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Recommended dilution: WB:1:500-2000, IHC:1:20-1:200. Researchers should empirically determine the suitability of the PPAP2C plpp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPAP2C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
