Western Blot (WB)
(Western blot analysis of anti-PPAP2C Antibody (C-term) in NCI-H460 cell line lysates (35ug/lane).PPAP2C(arrow) was detected using the purified Pab.)
Rabbit anti-Human PPAP2C Polyclonal Antibody | anti-PPAP2C antibody
PPAP2C, CT (Lipid Phosphate Phosphohydrolase 2, Phosphatidic Acid Phosphatase 2c, PAP-2c, PAP2c, Phosphatidate Phosphohydrolase Type 2c, PAP2-gamma, PAP2-G, LPP2)
Purified by ammonium sulfate precipitation.
Purified by ammonium sulfate precipitation.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100
Western Blot (WB)
(Western blot analysis of anti-PPAP2C Antibody (C-term) in NCI-H460 cell line lysates (35ug/lane).PPAP2C(arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of anti-PPAP2C Antibody (C-term) in NCI-H460 cell line lysates (35ug/lane).PPAP2C(arrow) was detected using the purified Pab.)
Flow Cytometry (FC/FACS)
(PPAP2C Antibody (C-term) flow cytometric analysis of NCI-H460 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(PPAP2C Antibody (C-term) flow cytometric analysis of NCI-H460 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B). All three proteins contain 6 transmembrane regions, and a consensus N-glycosylation site. This protein has been shown to possess membrane associated PAP activity. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
Uniprot Description
PPAP2C: Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1- phosphate (S-1-P). The relative catalytic efficiency is PA > C-1-P > LPA > S-1-P. Belongs to the PA-phosphatase related phosphoesterase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Lipid Metabolism - ether lipid; Lipid Metabolism - sphingolipid; Phosphatase, lipid; Membrane protein, integral; EC 3.1.3.4; Motility/polarity/chemotaxis; Membrane protein, multi-pass; Lipid Metabolism - glycerolipid; Lipid Metabolism - glycerophospholipid
Chromosomal Location of Human Ortholog: 19p13
Cellular Component: membrane; integral to membrane; plasma membrane
Molecular Function: phosphatidate phosphatase activity; phosphoprotein phosphatase activity
Biological Process: sphingolipid metabolic process; sphingolipid biosynthetic process; dephosphorylation
Research Articles on PPAP2C
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Product Notes
The PPAP2C ppap2c (Catalog #AAA623660) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PPAP2C, CT (Lipid Phosphate Phosphohydrolase 2, Phosphatidic Acid Phosphatase 2c, PAP-2c, PAP2c, Phosphatidate Phosphohydrolase Type 2c, PAP2-gamma, PAP2-G, LPP2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PPAP2C can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: ELISA: 1:1,000 Western Blot: 1:50-1:100. Researchers should empirically determine the suitability of the PPAP2C ppap2c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPAP2C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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