Western Blot (WB)
(Western Blot: Sample: Mouse Brain Tissue.)
Rabbit anti-Mouse Leptin Receptor Polyclonal Antibody | anti-LEPR antibody
Polyclonal Antibody to Leptin Receptor (LEPR)
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: Sample: Mouse Brain Tissue.)
Western Blot (WB)
(Western Blot: Sample: Mouse Brain Tissue.)
Western Blot (WB)
(Western Blot: Sample: Recombinant LEPR, Mouse.)
Western Blot (WB)
(Western Blot: Sample: Recombinant LEPR, Mouse.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Lung Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Lung Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Uterus Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Uterus Tissue.)
NCBI and Uniprot Product Information
Uniprot Description
LEPR: the receptor for leptin (obesity factor). A single-transmembrane-domain receptor of the cytokine receptor family. On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Five alternatively spliced transcript variants have been reported.
Protein type: Membrane protein, integral; Receptor, cytokine
Chromosomal Location of Human Ortholog: 4 C6|4 46.96 cM
Cellular Component: extracellular region; extracellular space; integral component of membrane; integral component of plasma membrane; membrane; plasma membrane; receptor complex
Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; identical protein binding; leptin receptor activity; peptide hormone binding; protein binding; protein-hormone receptor activity; transmembrane receptor activity
Biological Process: angiogenesis; bone growth; cholesterol metabolic process; eating behavior; glucose homeostasis; leptin-mediated signaling pathway; negative regulation of autophagy; negative regulation of eating behavior; negative regulation of gluconeogenesis; negative regulation of hydrolase activity; negative regulation of locomotor rhythm; phagocytosis; positive regulation of MAPK cascade; regulation of bone remodeling; regulation of energy homeostasis; regulation of metabolic process; response to leptin; sexual reproduction; signal transduction; T cell differentiation
Research Articles on LEPR
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Product Notes
The LEPR lepr (Catalog #AAA2027411) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Leptin Receptor (LEPR) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Leptin Receptor can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the LEPR lepr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Leptin Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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