Western Blot (WB)
(Western Blot analysis of LASS2 expression in transfected 293T cell line by LASS2 polyclonal antibody. Lane 1: LASS2 transfected lysate (44.9kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human LASS2 Polyclonal Antibody | anti-LASS2 antibody
LASS2 (Ceramide Synthase 2, CerS2, LAG1 Longevity Assurance Homolog 2, SP260, Tumor Metastasis-suppressor Gene 1 Protein, CERS2, TMSG1, FLJ10243, L3, MGC987) APC
Western Blot (WB)
(Western Blot analysis of LASS2 expression in transfected 293T cell line by LASS2 polyclonal antibody. Lane 1: LASS2 transfected lysate (44.9kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of LASS2 expression in transfected 293T cell line by LASS2 polyclonal antibody. Lane 1: LASS2 transfected lysate (44.9kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
Uniprot Description
Function: Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis.
Subunit structure: Interacts with ATP6V0C, ASGR1, ASGR2 and SLC22A1/OCT1. Interacts with ELOV1, HSD17B12 and TECR. Ref.1 Ref.15
Subcellular location: Nucleus membrane; Multi-pass membrane protein
Potential. Endoplasmic reticulum membrane; Multi-pass membrane protein
By similarity.
Tissue specificity: Expressed in kidney, liver, brain, heart, placenta and lung. Ref.1
Sequence similarities: Contains 1 homeobox DNA-binding domain.Contains 1 TLC (TRAM/LAG1/CLN8) domain.
Sequence caution: The sequence BAA91505.1 differs from that shown. Reason: Erroneous initiation.
Research Articles on LASS2
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Product Notes
The LASS2 cers2 (Catalog #AAA6384071) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LASS2 (Ceramide Synthase 2, CerS2, LAG1 Longevity Assurance Homolog 2, SP260, Tumor Metastasis-suppressor Gene 1 Protein, CERS2, TMSG1, FLJ10243, L3, MGC987) APC reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LASS2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the LASS2 cers2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LASS2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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