Western Blot
(Western blot analysis on K562-AO2 cell lysates using anti-lass2 monoclonal antibody.)
anti-Human LASS2 Antibody | anti-LASS2 antibody
LASS2 Antibody
Gene Names
CERS2; L3; LASS2; SP260; TMSG1
Reactivity
Human
Applications
Western Blot
Purity
Affinity Purified
Synonyms
LASS2; LASS2 Antibody; anti-LASS2 antibody
Reactivity
Human
Clone Number
B3-2
Specificity
This antibody is produced by immunizing mice with purified human IgG.
Purity/Purification
Affinity Purified
Form/Format
In 1*TBS (pH7.4), 0.5%BSA, 40%Glycerol.
Sequence Length
380
Applicable Applications for anti-LASS2 antibody
Western Blot (WB)
Application Notes
WB: 1:500~1:1,000
Cellular Localization
Nuclear Membrane
Positive Control
K562-AO2
Preparation and Storage
Store at +4 degree C after thawing. Aliquot store at-20 degree C or-80 degree C. Avoid repeated freeze/thaw cycles.
Western Blot
(Western blot analysis on K562-AO2 cell lysates using anti-lass2 monoclonal antibody.)
Western Blot
(Western blot analysis on K562-AO2 cell lysates using anti-lass2 monoclonal antibody.)
Related Product Information for anti-LASS2 antibody
The LAG1 gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described.
References
"Cloning, mapping, and characterization of a human homologue of the yeast longevity assurance gene LAG1."Pan H., Qin W.-X., Huo K.-K., Wan D.-F., Yu Y., Xu Z.-G., Hu Q.-D., Gu K.T., Zhou X.-M., Jiang H.-Q., Zhang P.-P., Huang Y., Li Y.-Y., Gu J.-R.Genomics 77:58-64(2001). "Expression of LASS2 controlled by LAG1 or ADH1 promoters cannot functionally complement Lag1p" Yu, Y., Lu, H., Pan, H., Ma, J.H., Ding, Z.J. and Li, Y.Y. Microbiol. Res. 161: 203-211.(2006).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
40kDa
NCBI Official Full Name
ceramide synthase 2
NCBI Official Synonym Full Names
ceramide synthase 2
NCBI Official Symbol
CERS2
NCBI Official Synonym Symbols
L3; LASS2; SP260; TMSG1
NCBI Protein Information
ceramide synthase 2
UniProt Protein Name
Ceramide synthase 2
UniProt Gene Name
CERS2
UniProt Synonym Gene Names
LASS2; TMSG1; CerS2
NCBI Description
This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
Uniprot Description
Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis.
Research Articles on LASS2
Similar Products
Product Notes
The LASS2 cers2 (Catalog #AAA850687) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The LASS2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LASS2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500~1:1,000. Researchers should empirically determine the suitability of the LASS2 cers2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LASS2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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