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Western Blot/Blotting (Western blot analysis using LAG1 longevity assurance homolog 2 at 10ug/ml on human placenta lysate 14 ug/lane. Lane A] antibody alone, Lane B] conjugate alone. Visualized using Pierce West Femto substrate system. Anti Rabbit secondary used at 1:10K dilution . Exposure for 5 minutes)

Rabbit anti-Human Lass2 Polyclonal Antibody | anti-Lass2 antibody

Lass2

Gene Names
CERS2; L3; LASS2; SP260; TMSG1
Reactivity
Human
Applications
Western Blot
Purity
Ammonium Sulfate Precipitation
Synonyms
Lass2; Polyclonal Antibody; LAG1 longevity assurance homolog 2; Tumor metastasis-suppressor gene 1 protein; SP260; anti-Lass2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Ammonium Sulfate Precipitation
Form/Format
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Sequence Length
380
Applicable Applications for anti-Lass2 antibody
Western Blot (WB)
Immunogen
Synthetic peptide derived from human Lass2 protein
Positive Control
liver and kidney
Preparation and Storage
Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles

Western Blot/Blotting

(Western blot analysis using LAG1 longevity assurance homolog 2 at 10ug/ml on human placenta lysate 14 ug/lane. Lane A] antibody alone, Lane B] conjugate alone. Visualized using Pierce West Femto substrate system. Anti Rabbit secondary used at 1:10K dilution . Exposure for 5 minutes)

Western Blot/Blotting (Western blot analysis using LAG1 longevity assurance homolog 2 at 10ug/ml on human placenta lysate 14 ug/lane. Lane A] antibody alone, Lane B] conjugate alone. Visualized using Pierce West Femto substrate system. Anti Rabbit secondary used at 1:10K dilution . Exposure for 5 minutes)
Related Product Information for anti-Lass2 antibody
LASS2, a human homologue of the yeast longevity assurance gene LAG1 is highly expressed in liver and kidney as compared to the expression of the human LAG1 homologue LAG1Hs-1. LASS2 is located on chromosome 1q11. The LASS2 protein interacts with several membrane-associated receptors or transporters. LASS2 protein inhibits the colony formation of human hepatoma cells in vitro, which suggests that this gene may be involved in the regulation of cell growth.
Product Categories/Family for anti-Lass2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44876
NCBI Official Full Name
ceramide synthase 2
NCBI Official Synonym Full Names
ceramide synthase 2
NCBI Official Symbol
CERS2
NCBI Official Synonym Symbols
L3; LASS2; SP260; TMSG1
NCBI Protein Information
ceramide synthase 2; LAG1 longevity assurance 2; LAG1 homolog, ceramide synthase 2; tumor metastasis-suppressor gene 1 protein; longevity assurance (LAG1, S. cerevisiae) homolog 2
UniProt Protein Name
Ceramide synthase 2
UniProt Gene Name
CERS2
UniProt Synonym Gene Names
LASS2; TMSG1; CerS2
UniProt Entry Name
CERS2_HUMAN

NCBI Description

This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

Uniprot Description

Function: Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis.

Subunit structure: Interacts with ATP6V0C, ASGR1, ASGR2 and SLC22A1/OCT1. Interacts with ELOV1, HSD17B12 and TECR. Ref.1 Ref.15

Subcellular location: Nucleus membrane; Multi-pass membrane protein

Potential. Endoplasmic reticulum membrane; Multi-pass membrane protein

By similarity.

Tissue specificity: Expressed in kidney, liver, brain, heart, placenta and lung. Ref.1

Sequence similarities: Contains 1 homeobox DNA-binding domain.Contains 1 TLC (TRAM/LAG1/CLN8) domain.

Sequence caution: The sequence BAA91505.1 differs from that shown. Reason: Erroneous initiation.

Research Articles on Lass2

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Product Notes

The Lass2 cers2 (Catalog #AAA395751) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Lass2 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Lass2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the Lass2 cers2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Lass2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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