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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human brain tissue using MBS7050875 at dilution of 1:100)

Rabbit anti-Human KCNG4 Polyclonal Antibody | anti-KCNG4 antibody

KCNG4 Antibody

Gene Names
KCNG4; KV6.3; KV6.4
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Immunofluorescence
Purity
>95%, Protein G purified
Synonyms
KCNG4; Polyclonal Antibody; KCNG4 Antibody; Potassium voltage-gated channel subfamily G member 4; Voltage-gated potassium channel subunit Kv6.4; KCNG3; anti-KCNG4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
519
Applicable Applications for anti-KCNG4 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
IHC: 1: 20-1: 200
IF: 1: 50-1: 200
Immunogen
Recombinant Human Potassium voltage-gated channel subfamily G member 4 protein (1-218AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, PH 7.4
Conjugation
Non-conjugated
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-23322-R
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human brain tissue using MBS7050875 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human brain tissue using MBS7050875 at dilution of 1:100)

Immunofluorescence (IF)

(Immunofluorescent analysis of HepG2 cells using MBS7050875 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Immunofluorescence (IF) (Immunofluorescent analysis of HepG2 cells using MBS7050875 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Related Product Information for anti-KCNG4 antibody
Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 (PubMed: 19074135).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
29,334 Da
NCBI Official Full Name
potassium voltage-gated channel subfamily G member 4
NCBI Official Synonym Full Names
potassium voltage-gated channel modifier subfamily G member 4
NCBI Official Symbol
KCNG4
NCBI Official Synonym Symbols
KV6.3; KV6.4
NCBI Protein Information
potassium voltage-gated channel subfamily G member 4
UniProt Protein Name
Potassium voltage-gated channel subfamily G member 4
UniProt Gene Name
KCNG4
UniProt Synonym Gene Names
KCNG3
UniProt Entry Name
KCNG4_HUMAN

NCBI Description

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member functions as a modulatory subunit. The gene has strong expression in brain. Multiple alternatively spliced variants have been found in normal and cancerous tissues. [provided by RefSeq, Jul 2008]

Uniprot Description

KCNG4: Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values. Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.4/KCNG4 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 16q24.1

Cellular Component: plasma membrane; voltage-gated potassium channel complex

Molecular Function: delayed rectifier potassium channel activity

Research Articles on KCNG4

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Product Notes

The KCNG4 kcng4 (Catalog #AAA7050875) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KCNG4 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KCNG4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF). IHC: 1: 20-1: 200 IF: 1: 50-1: 200. Researchers should empirically determine the suitability of the KCNG4 kcng4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KCNG4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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