Rabbit JAK2 Polyclonal Antibody | anti-jak2b antibody
JAK2, phosphorylated (Tyr1007) (Tyrosine-protein Kinase JAK2, Janus Kinase 2, JAK-2)
Gene Names
jak2b; jak2; JAK2bCA
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
JAK2; Polyclonal Antibody; phosphorylated (Tyr1007) (Tyrosine-protein Kinase JAK2; Janus Kinase 2; JAK-2); Anti -JAK2; anti-jak2b antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human JAK2 when phosphorylated at tyrosine 1007. Species Crossreactivity: mouse, rat.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Applicable Applications for anti-jak2b antibody
Immunohistochemistry (IHC)
Application Notes
Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry: 1:50-1:100
Dilution: Immunohistochemistry: 1:50-1:100
Immunogen
Synthetic phosphopeptide corresponding to human JAK2 around the phosphorylation site of tyrosine 1007 (K-E-YP-Y-K).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-jak2b antibody
JAK 2 (Janus Activating Kinase 2) is one of a number of related tyrosine kinases involved in cytoplasmic signal transduction. In response to a variety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine residues as well as perhaps one or more serine residues. The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activators of transcription) proteins, which dimerize and translocate to the nucleus. Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including ISGs (interferon-stimulated genes). JAK 2 plays an essential role in Interferon-gamma signaling.
Product Categories/Family for anti-jak2b antibody
NCBI and Uniprot Product Information
Research Articles on jak2b
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Product Notes
The jak2b (Catalog #AAA625793) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The JAK2, phosphorylated (Tyr1007) (Tyrosine-protein Kinase JAK2, Janus Kinase 2, JAK-2) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's JAK2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Suitable for use in Immunohistochemistry. Dilution: Immunohistochemistry: 1:50-1:100. Researchers should empirically determine the suitability of the jak2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "JAK2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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