SDS-Page
(Proteins from 3T3-L1 cell extracts were resolved by SDS-PAGE and transferred to PVDF. Membranes were incubated with 0.5 ug/mL of rabbit polyclonal anti-JAK 2 antibody)
Rabbit anti-Human JAK2 Polyclonal Antibody | anti-jak2b antibody
JAK2 (Janus Kinase 2)
Gene Names
jak2b; jak2; JAK2bCA
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified from rabbit serum by epitope-specific affinity chromatography.
Synonyms
JAK2; Polyclonal Antibody; JAK2 (Janus Kinase 2); Anti -JAK2 (Janus Kinase 2); anti-jak2b antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes JAK 2 (130kD) from a number of tissues, including mouse 3T3-L1 cells, rat adipocytes and A431 human carcinoma cells. A minor degradation product at approximately 92kD might also be visible in some cell and tissue preparations. Does not crossreact with other JAK or related proteins. Species sequence homology: rat and mouse
Purity/Purification
Affinity Purified
Purified from rabbit serum by epitope-specific affinity chromatography.
Purified from rabbit serum by epitope-specific affinity chromatography.
Form/Format
Supplied as a liquid in Dulbecco's PBS, (without magnesium and calcium), pH 7.3, 50% glycerol, 1mg/ml BSA.
Applicable Applications for anti-jak2b antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 0.5-1ug/ml
Dilution: Western Blot: 0.5-1ug/ml
Immunogen
ynthetic peptide derived from a C-terminal region of human JAK 2.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SDS-Page
(Proteins from 3T3-L1 cell extracts were resolved by SDS-PAGE and transferred to PVDF. Membranes were incubated with 0.5 ug/mL of rabbit polyclonal anti-JAK 2 antibody)
SDS-Page
(Proteins from 3T3-L1 cell extracts were resolved by SDS-PAGE and transferred to PVDF. Membranes were incubated with 0.5 ug/mL of rabbit polyclonal anti-JAK 2 antibody)
Related Product Information for anti-jak2b antibody
JAK 2 (Janus Activating Kinase 2) is one of a number of related tyrosine kinases involved in cytoplasmic signal transduction. In response to a variety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine residues as well as perhaps one or more serine residues. The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activators of transcription) proteins, which dimerize and translocate to the nucleus. Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including ISGs (interferon-stimulated genes). JAK 2 plays an essential role in Interferon-gamma signaling.
Product Categories/Family for anti-jak2b antibody
NCBI and Uniprot Product Information
Research Articles on jak2b
Similar Products
Product Notes
The jak2b (Catalog #AAA621710) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The JAK2 (Janus Kinase 2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's JAK2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: Western Blot: 0.5-1ug/ml. Researchers should empirically determine the suitability of the jak2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "JAK2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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