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Rabbit IgG Polyclonal Antibody | anti-IgG antibody
IgG/FITC, Rpab
Applications
Immunohistochemistry
Synonyms
IgG; Polyclonal Antibody; IgG/FITC; Rpab; anti-IgG antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Form/Format
Concentrate or Prediluted
Sequence Length
476
Applicable Applications for anti-IgG antibody
Immunohistochemistry (IHC) Frozen/Paraffin
Immunogen
Purified human IgG gamma chain.
Localization
Cytoplasmic
Control
Tonsil, Lymph Node, Kidney, Spleen
Preparation and Storage
Store at 2-8 degree C in the dark.
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Immunofluorescence (IF)
(IF of IgG)
Immunofluorescence (IF)
(IF of IgG)
Related Product Information for anti-IgG antibody
IgG is a monomeric immunoglobulin, comprised of two heavy chains and two light chains. This is the most abundant immunoglobulin and is approximately equally distributed in blood and tissue liquids, constituting 75% of serum immunoglobulins in humans. This is the only isotype that can pass through the placenta and bind to many kinds of pathogens. IgG protects the body against them by complement activation (classic pathway), opsonization for phagocytosis and neutralization of their toxins. There are 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%).
IgG antibody reacts with surface immunoglobulin IgG gamma chains. This antibody is useful when identifying Leukemias, Plasmacytomas, and B-cell lineage derived Hodgkin’s Lymphomas. Due to the restricted expression of heavy and light chains in these diseases, demonstration of B-cell Lymphomas is possible with clonal gene-rearrangement studies. Lupus nephritis is an inflammation of the kidneys caused by Systemic Lupus Erythematosus. Immunofluorescence reveals positively for IgG, IgA, IgM, C3, and C1q. Clinically, hematuria and proteinuria are present, with or without nephrotic syndromes. Mesangial IgG glomerulonephritis has been recently recognized as a distinct type of glomerulonephritis. The morphologic criteria detected in these patients included mesangial dense deposits by ultrastructural studies, which were predominantly positive for IgG by immunofluorescence.
IgG antibody reacts with surface immunoglobulin IgG gamma chains. This antibody is useful when identifying Leukemias, Plasmacytomas, and B-cell lineage derived Hodgkin’s Lymphomas. Due to the restricted expression of heavy and light chains in these diseases, demonstration of B-cell Lymphomas is possible with clonal gene-rearrangement studies. Lupus nephritis is an inflammation of the kidneys caused by Systemic Lupus Erythematosus. Immunofluorescence reveals positively for IgG, IgA, IgM, C3, and C1q. Clinically, hematuria and proteinuria are present, with or without nephrotic syndromes. Mesangial IgG glomerulonephritis has been recently recognized as a distinct type of glomerulonephritis. The morphologic criteria detected in these patients included mesangial dense deposits by ultrastructural studies, which were predominantly positive for IgG by immunofluorescence.
Product Categories/Family for anti-IgG antibody
NCBI and Uniprot Product Information
Similar Products
Product Notes
The IgG (Catalog #AAA370401) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IgG can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Frozen/Paraffin. Researchers should empirically determine the suitability of the IgG for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IgG, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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