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Rabbit Fibrinogen Polyclonal Antibody
Fibrinogen/FITC, RPab
Applications
Immunohistochemistry
Synonyms
Fibrinogen; Polyclonal Antibody; Fibrinogen/FITC; RPab; anti-Fibrinogen antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Form/Format
Concentrate or Prediluted
Sequence Length
126
Applicable Applications for anti-Fibrinogen antibody
Immunohistochemistry (IHC) Frozen/Paraffin
Immunogen
KLH conjugated synthetic peptidecorresponding to the N-terminus of human FGA.
Localization
Cytoplasmic
Control
Breast, Testis, Kidney, Pancreas, Salivary Gland, Skin, Fallopian Tube
Preparation and Storage
Store at 2-8 degree C in the dark.
Dilution Information
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Immunofluorescence (IF)
(IF of Fibrinogen)
Immunofluorescence (IF)
(IF of Fibrinogen)
Related Product Information for anti-Fibrinogen antibody
Fibrinogen (factor I) is a glycoprotein that circulates in the blood of vertebrates. During tissue and vascular injury, it is converted enzymatically by thrombin to fibrin and subsequently to a fibrin-based blood clot. Fibrinogen functions primarily to occlude blood vessels and thereby stop excessive bleeding. Fibrin also mediates blood platelet and endothelial cell spreading, tissue fibroblast proliferation, capillary tube formation, and angiogenesis and thereby functions to promote tissue revascularization, wound healing, and tissue repair.
Several disorders (Congenital afibrinogenemia, hypofibrinogenemia, Fibrinogen storage disease, hereditary fibrinogen Aa-Chain amyloidosis, congenital hypodysfibrinogenemia, Cryofibrinogenemia, acquired hypofibrinogenemia, Chronic Kidney Disease, etc.) in the quantity and/or quality of fibrinogen cause pathological bleeding, pathological blood clotting, and/or the deposition of fibrinogen in the liver, kidneys, and other tissues. Chronic kidney disease (CKD) patients have increased rates of bleeding as well as thrombosis. Fibrinogen and platelets combine to generate a mature clot, but in CKD platelets are dysfunctional.
Several disorders (Congenital afibrinogenemia, hypofibrinogenemia, Fibrinogen storage disease, hereditary fibrinogen Aa-Chain amyloidosis, congenital hypodysfibrinogenemia, Cryofibrinogenemia, acquired hypofibrinogenemia, Chronic Kidney Disease, etc.) in the quantity and/or quality of fibrinogen cause pathological bleeding, pathological blood clotting, and/or the deposition of fibrinogen in the liver, kidneys, and other tissues. Chronic kidney disease (CKD) patients have increased rates of bleeding as well as thrombosis. Fibrinogen and platelets combine to generate a mature clot, but in CKD platelets are dysfunctional.
Product Categories/Family for anti-Fibrinogen antibody
NCBI and Uniprot Product Information
Similar Products
Product Notes
The Fibrinogen (Catalog #AAA370398) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Fibrinogen can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Frozen/Paraffin. Researchers should empirically determine the suitability of the Fibrinogen for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Fibrinogen, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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