Rabbit anti-Human ICOSLG Polyclonal Antibody | anti-ICOSLG antibody

ICOSLG Polyclonal Antibody

Cat. Num. AAA9415279

• Gene Names: ICOSLG; B7H2; GL50; B7-H2; B7RP1; CD275; ICOSL; LICOS; B7RP-1; ICOS-L
• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Antigen Affinity Purified
• Synonyms: ICOSLG; Polyclonal Antibody; ICOSLG Polyclonal Antibody; B7 homolog 2; B7-H2; B7-like protein Gl50; B7-related protein 1; B7RP-1; CD275; B7H2; B7RP1; ICOSL; KIAA0653; anti-ICOSLG antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous level of total ICOSLG polyclonal antibody.
• Purity/Purification: Antigen Affinity Purified
• Form/Format: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 309

• Applicable Applications for anti-ICOSLG antibody: Immunohistochemistry (IHC)
• Application Notes: Immunohistochemistry: 1:20 - 1:200
• Immunogen: Recombinant Human ICOS ligand protein (19-256aa)
• Immunogen Type: Protein
• Preparation and Storage: Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human tonsil using at dilution of 1:100.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human epityphlon using at dilution of 1:100.)

Related Product Information for anti-ICOSLG antibody

Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells.Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).

Product Categories/Family for anti-ICOSLG antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 545688560
• NCBI GeneID: 23308
• NCBI Accession #: NP_001269979.1
• NCBI GenBank Nucleotide #: NM_001283050.1
• UniProt Accession #: O75144; Q9HD18; Q9NRQ1; A8MUZ1
• Molecular Weight: 20,120 Da
• NCBI Official Full Name: ICOS ligand isoform b
• NCBI Official Synonym Full Names: inducible T-cell co-stimulator ligand
• NCBI Official Symbol: ICOSLG
• NCBI Official Synonym Symbols: B7H2; GL50; B7-H2; B7RP1; CD275; ICOSL; LICOS; B7RP-1; ICOS-L
• NCBI Protein Information: ICOS ligand
• UniProt Protein Name: ICOS ligand
• Protein Family: ICOS ligand
• UniProt Gene Name: ICOSLG
• UniProt Synonym Gene Names: B7H2; B7RP1; ICOSL; KIAA0653; B7-H2; B7RP-1
• UniProt Entry Name: ICOSL_HUMAN

Uniprot Description

ICOSLG: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co- stimulating memory T-cell function. Belongs to the immunoglobulin superfamily. BTN/MOG family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: plasma membrane

Molecular Function: receptor binding

Biological Process: positive regulation of activated T cell proliferation; T cell costimulation