SDS-Page
(Figure 1. Human B7H2 Protein, mFc-His Tag on SDS-PAGE under reducing condition.)
B7-H2 recombinant protein
Recombinant human B7-H2 protein with C-terminal mouse Fc and 6xHis tag
Applications
Western Blot
Purity
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Synonyms
B7-H2; Recombinant human B7-H2 protein with C-terminal mouse Fc and 6xHis tag; Human B7-H2 Protein; mFc-His Tag; ICOSLG; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; LICOS; ICOS ligand; B7-H2 recombinant protein
Host
HEK293 cells
Purity/Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Form/Format
Lyophilized from sterile PBS, pH 7.4. Normally 5%-36% trehalose is added as protectants before lyophilization.
Sequence
B7H2(Asp19-Thr256)+mFc(Pro99-Lys330)
Applicable Applications for B7-H2 recombinant protein
Western Blot (WB)
Source
Human
Conjugation
C-Mouse Fc and 6xHis tag
Reconstitution
Reconstitute with deionized water
Preparation and Storage
Store at -80 degree C for 12 months (Avoid repeated freezing and thawing)
Shipping: Blue Ice
Shipping: Blue Ice
SDS-Page
(Figure 1. Human B7H2 Protein, mFc-His Tag on SDS-PAGE under reducing condition.)
SDS-Page
(Figure 1. Human B7H2 Protein, mFc-His Tag on SDS-PAGE under reducing condition.)
Related Product Information for B7-H2 recombinant protein
Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2.The protein is the ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
20,120 Da
NCBI Official Full Name
ICOS ligand
NCBI Official Symbol
LOC102723996
NCBI Protein Information
ICOS ligand
UniProt Protein Name
ICOS ligand
UniProt Gene Name
ICOSLG
UniProt Synonym Gene Names
B7H2; B7RP1; ICOSL; KIAA0653; B7-H2; B7RP-1
Uniprot Description
Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function ().
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Product Notes
The B7-H2 icoslg (Catalog #AAA188085) is a Recombinant Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's B7-H2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the B7-H2 icoslg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: B7H2(Asp19 -Thr256)+m Fc(Pro99-L ys330). It is sometimes possible for the material contained within the vial of "B7-H2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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