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Testing Data

Rabbit HMGCS1 Polyclonal Antibody | anti-HMGCS1 antibody

HMGCS1 Antibody

Gene Names
HMGCS1; HMGCS
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunofluorescence
Purity
Antigen affinity purification
Synonyms
HMGCS1; Polyclonal Antibody; HMGCS1 Antibody; HMGCS; MGC90332; anti-HMGCS1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Sequence Length
520
Applicable Applications for anti-HMGCS1 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes
WB: 1:1000-1:10000
IF: 1:20-1:50
Immunogen
Fusion protein of HMGCS1
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-32422 / sc-32423 / sc-33829
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles

Testing Data

Testing Data

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
57,294 Da
NCBI Official Full Name
hydroxymethylglutaryl-CoA synthase, cytoplasmic
NCBI Official Synonym Full Names
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
NCBI Official Symbol
HMGCS1
NCBI Official Synonym Symbols
HMGCS
NCBI Protein Information
hydroxymethylglutaryl-CoA synthase, cytoplasmic; 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase; 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)
UniProt Protein Name
Hydroxymethylglutaryl-CoA synthase, cytoplasmic
UniProt Gene Name
HMGCS1
UniProt Synonym Gene Names
HMGCS; HMG-CoA synthase
UniProt Entry Name
HMCS1_HUMAN

Uniprot Description

HMGCS1: This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. Belongs to the HMG-CoA synthase family.

Protein type: Transferase; EC 2.3.3.10; Carbohydrate Metabolism - butanoate; Lipid Metabolism - synthesis and degradation of ketone bodies; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis

Chromosomal Location of Human Ortholog: 5p14-p13

Cellular Component: nucleoplasm; cytoplasm; plasma membrane; cytosol; nucleus

Molecular Function: protein homodimerization activity; organic acid binding; hydroxymethylglutaryl-CoA synthase activity; drug binding; isomerase activity

Biological Process: response to drug; response to purine; response to vitamin E; response to tellurium ion; isoprenoid biosynthetic process; male gonad development; response to lipoprotein stimulus; cellular lipid metabolic process; lipid metabolic process; brain development; liver development; cholesterol biosynthetic process; response to low light intensity

Research Articles on HMGCS1

Similar Products

Product Notes

The HMGCS1 hmgcs1 (Catalog #AAA2524387) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HMGCS1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HMGCS1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunofluorescence (IF). WB: 1:1000-1:10000 IF: 1:20-1:50. Researchers should empirically determine the suitability of the HMGCS1 hmgcs1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HMGCS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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