Rabbit anti-Human ANKRD17 Polyclonal Antibody | anti-ANKRD17 antibody

ANKRD17 (Ankyrin Repeat Domain-containing Protein 17, Gene Trap Ankyrin Repeat Protein, Serologically Defined Breast Cancer Antigen NY-BR-16, GTAR, KIAA0697)

Cat. Num. AAA644000

• Gene Names: ANKRD17; GTAR; NY-BR-16
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: ANKRD17; Polyclonal Antibody; ANKRD17 (Ankyrin Repeat Domain-containing Protein 17; Gene Trap Ankyrin Repeat Protein; Serologically Defined Breast Cancer Antigen NY-BR-16; GTAR; KIAA0697); Anti -ANKRD17 (Ankyrin Repeat Domain-containing Protein 17; anti-ANKRD17 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human ANKRD17.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MEKATVPVAAATAAEGEGSPPAVAAVAGPPAAAEVGGGVGGSSRARSASSPRGMVRVCDLLLKKKPPQQQHHKAKRNRTCRPPSSSESSSDSDNSGGGGGGGGGGGGGGGTSSNNSEEEEDDDDEEEEVSEVESFILDQDDLENPMLETASKLLLSGTADGADLRTVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTANAGQSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYPNNLLSAPPPDVTQLTPPSHDLTDNIFPRLVC

• Applicable Applications for anti-ANKRD17 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Immunogen: Full length human ANKRD17, aa1-751 (AAH43394.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of ANKRD17 expression in transfected 293T cell line by ANKRD17 polyclonal antibody. Lane 1: ANKRD17 transfected lysate (77.8kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-ANKRD17 antibody

Earliest specific in situ marker of hepatic differentiation during embryogenesis, useful for characterization of inductive events involved in hepatic specification. Target of enterovirus 71 which is the major etiological agent of HFMD (hand, foot and mouth disease).

Product Categories/Family for anti-ANKRD17 antibody

Antibodies; Abs to Membrane Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 38683816
• NCBI GeneID: 26057
• NCBI Accession #: NP_942592.1
• NCBI GenBank Nucleotide #: NM_198889.1
• UniProt Accession #: O75179; Q6PJ85; Q6PK85; Q6PKA2; Q86XI3; Q8NDR5; Q96I86; Q9H288; Q9H6J9; G5E964
• Molecular Weight: 274,258 Da
• NCBI Official Full Name: ankyrin repeat domain-containing protein 17 isoform b
• NCBI Official Synonym Full Names: ankyrin repeat domain 17
• NCBI Official Symbol: ANKRD17
• NCBI Official Synonym Symbols: GTAR; NY-BR-16
• NCBI Protein Information: ankyrin repeat domain-containing protein 17; gene trap ankyrin repeat protein; serologically defined breast cancer antigen NY-BR-16
• UniProt Protein Name: Ankyrin repeat domain-containing protein 17
• Protein Family: Ankyrin repeat domain-containing protein
• UniProt Gene Name: ANKRD17
• UniProt Synonym Gene Names: GTAR; KIAA0697
• UniProt Entry Name: ANR17_HUMAN

NCBI Description

This gene encodes a protein with ankyrin repeats, which are associated with protein-protein interactions. Studies in mice suggest that this protein is involved in liver development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

ANKRD17: the earliest specific in situ marker of hepatic differentiation during embryogenesis, useful for characterization of inductive events involved in hepatic specification. Target of enterovirus 71 which is the major etiological agent of HFMD (hand, foot and mouth disease). Interacts with VP1 capsid protein of enterovirus 71 (EV71). Five alternatively processed human isoforms have been described.

Protein type: Cell development/differentiation

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: membrane; cytoplasm; nucleus; chromatin

Molecular Function: protein binding; chromatin binding

Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; viral reproduction; defense response to bacterium; positive regulation of cell cycle; innate immune response; negative regulation of smooth muscle cell differentiation; blood vessel maturation; regulation of DNA replication