Western Blot (WB)
(Sample Data: Representative western blot with Anti-HDAC7 (1:1000) using 25 ng of human recombinant proteins HDAC1 to HDAC11.)
Rabbit HDAC7 Polyclonal Antibody | anti-HDAC7 antibody
Anti-HDAC7
Reactivity
HDAC7 from other species may also be detectable.
Applications
Western Blot
Purity
Affinity Chromatography
Synonyms
HDAC7; Polyclonal Antibody; Anti-HDAC7; anti-HDAC7 antibody
Host
Rabbit
Reactivity
HDAC7 from other species may also be detectable.
Clonality
Polyclonal
Specificity
Recognizes the human HDAC7 protein
Purity/Purification
Affinity Chromatography
Form/Format
PBS pH7.4, 50% glycerol
Applicable Applications for anti-HDAC7 antibody
Western Blot (WB)
Application Notes
WB: 1:1000
Immunogen
Synthetic peptide corresponding to c-terminus of human HDAC7 conjugated to KLH.
Preparation and Storage
Store at 4 degree C (add 0.1% NaN3) for several months, and at -20 degree C for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For optimal performance, avoid repeated handling and multiple freeze/thaw cycles.
Western Blot (WB)
(Sample Data: Representative western blot with Anti-HDAC7 (1:1000) using 25 ng of human recombinant proteins HDAC1 to HDAC11.)
Western Blot (WB)
(Sample Data: Representative western blot with Anti-HDAC7 (1:1000) using 25 ng of human recombinant proteins HDAC1 to HDAC11.)
Related Product Information for anti-HDAC7 antibody
HDAC7 or Histone deacetylase 7 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. The protein encoded by HDAC7 gene has sequence homology to members of the histone deacetylase family whose protein promotes repression mediated via the transcriptional co-repressor SMRT (1). HDAC7 interacts with beta-catenin keeping endothelial cells in a low proliferation stage. HDAC7 regulates NUR77 and apoptosis in developing thymocytes (2). HDAC7 is expressed in human osteoarthritis that contributes to cartilage degradation via promoting MMP-13 gene expression.
Product Categories/Family for anti-HDAC7 antibody
References
1. Kao, H. Y. et.al: Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression. Genes Dev. 14: 55-66, 2000.
2. Dequiedt, F. et.al: HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis. Immunity 18: 687-698, 2003.
2. Dequiedt, F. et.al: HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis. Immunity 18: 687-698, 2003.
Similar Products
Product Notes
The HDAC7 (Catalog #AAA516005) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-HDAC7 reacts with HDAC7 from other species may also be detectable. and may cross-react with other species as described in the data sheet. AAA Biotech's HDAC7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1000. Researchers should empirically determine the suitability of the HDAC7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HDAC7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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