Rabbit anti-Human, Rat GPR85 Polyclonal Antibody | anti-GPR85 antibody

GPR85 Polyclonal Antibody

Cat. Num. AAA3006926

• Gene Names: GPR85; SREB; SREB2
• Reactivity: Human, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: GPR85; Polyclonal Antibody; GPR85 Polyclonal Antibody; Probable G-protein coupled receptor 85; Super conserved receptor expressed in brain 2; SREB2; anti-GPR85 antibody

• Host: Rabbit
• Reactivity: Human, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: GPR85 polyclonal antibody detects endogenous levels of GPR85 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 370

• Applicable Applications for anti-GPR85 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: A synthetic peptide corresponding to residues in Human GPR85
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of GPR85 polyclonal antibody at 1:500 dilutionLane1:A549 whole cell lysateLane2:H9C2 whole cell lysate)

Related Product Information for anti-GPR85 antibody

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways.G protein-coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR85 (G protein-coupled receptor 85), also designated SREB2 (super conserved receptor expressed in brain 2), is a 370 amino acid multi-pass membrane protein that functions as an orphan receptor and belongs to the GPR family. Highly expressed in testis and brain, GPR85 is found at lower levels in spleen, placenta and small intestine, and is encoded by a gene that maps to human chromosome 7q31.

NCBI and Uniprot Product Information

• NCBI GI #: 153266936
• NCBI GeneID: 54329
• NCBI Accession #: NP_061843.3
• NCBI GenBank Nucleotide #: NP_061843.3
• UniProt Accession #: P60893
• Molecular Weight: ~ 42kDa
• NCBI Official Full Name: probable G-protein coupled receptor 85
• NCBI Official Synonym Full Names: G protein-coupled receptor 85
• NCBI Official Symbol: GPR85
• NCBI Official Synonym Symbols: SREB; SREB2
• NCBI Protein Information: probable G-protein coupled receptor 85
• UniProt Protein Name: Probable G-protein coupled receptor 85
• Protein Family: Probable G protein-coupled receptor
• UniProt Gene Name: GPR85
• UniProt Synonym Gene Names: SREB2
• UniProt Entry Name: GPR85_HUMAN

NCBI Description

Members of the G protein-coupled receptor (GPCR) family, such as GPR85, have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli, such as neurotransmitters, hormones, or light, induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins (Matsumoto et al., 2000 [PubMed 10833454]).[supplied by OMIM, Aug 2008]

Uniprot Description

GPR85: Orphan receptor. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral

Chromosomal Location of Human Ortholog: 7q31

Cellular Component: plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; signal transduction