Immunohistochemistry (IHC)
(Anti-GPR85 antibody IHC of human brain, neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit SREB / GPR85 Polyclonal Antibody | anti-SREB antibody
Rabbit Polyclonal to Human SREB / GPR85
Gene Names
GPR85; SREB; SREB2
Reactivity
Bat, Gibbon, Bovine, Chicken, Dog, Xenopus, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Orangutan, Pig, Rabbit, Rat, Zebrafish
Applications
Immunohistochemistry, Immunocytochemistry
Purity
Immunoaffinity Purified
Synonyms
SREB / GPR85; Polyclonal Antibody; Rabbit Polyclonal to Human SREB / GPR85; Anti-SREB / GPR85 Antibody (C-Terminus) IHC-plus; GPR85; G protein-coupled receptor 85; Rgpr85; SREB; Pkrcx1; SREB2; Human SREB; anti-SREB antibody
Host
Rabbit
Reactivity
Bat, Gibbon, Bovine, Chicken, Dog, Xenopus, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Orangutan, Pig, Rabbit, Rat, Zebrafish
Clonality
Polyclonal
Specificity
Human GPR85. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except NLRC3 (40%).
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
370
Applicable Applications for anti-SREB antibody
Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC)
Application Notes
ICC, IHC-P (9 - 17 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 20 amino acid peptide from C-terminus of human GPR85.
Immunogen Type
Synthetic peptide
Immunogen
SREB / GPR85 antibody was raised against synthetic 20 amino acid peptide from C-terminus of human GPR85. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Dog, Bat, Bovine, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Lizard, Xenopus, Stickleback, Pufferfish, Zebrafish (100%).
Antigen Modification
C-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Immunohistochemistry (IHC)
(Anti-GPR85 antibody IHC of human brain, neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-GPR85 antibody IHC of human brain, neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-SREB antibody
GPR85, a member of the SREB (Super-Conserved Receptor Expressed in Brain) family of GPCRs, is an Orphan-A GPCR with an unknown ligand. The rat counterpart of SREB2 is involved in the development of the cerebral cortex.
Product Categories/Family for anti-SREB antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
41,995 Da
NCBI Official Full Name
probable G-protein coupled receptor 85
NCBI Official Synonym Full Names
G protein-coupled receptor 85
NCBI Official Symbol
GPR85
NCBI Official Synonym Symbols
SREB; SREB2
NCBI Protein Information
probable G-protein coupled receptor 85; seven transmembrane helix receptor; super conserved receptor expressed in brain 2
UniProt Protein Name
Probable G-protein coupled receptor 85
UniProt Gene Name
GPR85
UniProt Synonym Gene Names
SREB2
UniProt Entry Name
GPR85_HUMAN
NCBI Description
Members of the G protein-coupled receptor (GPCR) family, such as GPR85, have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli, such as neurotransmitters, hormones, or light, induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins (Matsumoto et al., 2000 [PubMed 10833454]).[supplied by OMIM, Aug 2008]
Uniprot Description
GPR85: Orphan receptor. Belongs to the G-protein coupled receptor 1 family.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 7q31
Cellular Component: integral to membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; signal transduction
Research Articles on SREB
Similar Products
Product Notes
The SREB gpr85 (Catalog #AAA247457) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human SREB / GPR85 reacts with Bat, Gibbon, Bovine, Chicken, Dog, Xenopus, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Orangutan, Pig, Rabbit, Rat, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's SREB / GPR85 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC). ICC, IHC-P (9 - 17 ug/ml). Researchers should empirically determine the suitability of the SREB gpr85 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SREB / GPR85, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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