anti-Human GASP1 Antibody | anti-GASP1 antibody

GASP1 Antibody

Cat. Num. AAA851604

• Gene Names: GPRASP1; GASP; GASP1; GASP-1
• Reactivity: Human
• Applications: Immunohistochemistry, Immunofluorescence, ELISA
• Purity: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: GASP1; GASP1 Antibody; G-protein coupled receptor-associated sorting protein 1; GASP-1; anti-GASP1 antibody

• Reactivity: Human
• Specificity: GASP1 antibody detects endogenous levels of total GASP1 protein.
• Purity/Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Sequence Length: 1395

• Applicable Applications for anti-GASP1 antibody: Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
• Application Notes: IHC: 1:50-1:100; IF: 1:100-1:500; ELISA: 1:10000
• Immunogen: The antiserum was produced against synthesized peptide derived from internal of human GASP1.
• Preparation and Storage: Store at-20 degree C for 1 year.

Testing Data

(Peptide-+)

Immunohistochemistry (IHC)

(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue using GASP1 antibody. Immunofluorescence analysis of A549 cells, using GASP1 antibody.)

Product Categories/Family for anti-GASP1 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells

References

Ishikawa K., DNA Res. 4:307-313(1997). Ross M.T., Nature 434:325-337(2005). Whistler J.L., Science 297:615-620(2002).

NCBI and Uniprot Product Information

• NCBI GI #: 150378489
• NCBI GeneID: 9737
• NCBI Accession #: NP_001092880.1
• NCBI GenBank Nucleotide #: NM_001099410.1
• UniProt Accession #: Q5JY77; O43168; Q96LA1
• Molecular Weight: 156,865 Da
• NCBI Official Full Name: G-protein coupled receptor-associated sorting protein 1
• NCBI Official Synonym Full Names: G protein-coupled receptor associated sorting protein 1
• NCBI Official Symbol: GPRASP1
• NCBI Official Synonym Symbols: GASP; GASP1; GASP-1
• NCBI Protein Information: G-protein coupled receptor-associated sorting protein 1
• UniProt Protein Name: G-protein coupled receptor-associated sorting protein 1
• UniProt Gene Name: GPRASP1
• UniProt Synonym Gene Names: GASP; KIAA0443; GASP-1

NCBI Description

This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, May 2010]

Uniprot Description

Modulates lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN2.