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Testing Data

anti-Human, Mouse CTSD Antibody | anti-CTSD antibody

CTSD Antibody

Gene Names
CTSD; CPSD; CLN10; HEL-S-130P
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
CTSD; CTSD Antibody; CATD; Cathepsin D; Cathepsin D heavy chain; Cathepsin D light chain; ceroid-lipofuscinosis; neuronal 10; CLN10; CPSD; lysosomal aspartyl peptidase; lysosomal aspartyl protease; MGC2311; anti-CTSD antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse
Specificity
CTSD antibody detects endogenous levels of total CTSDprotein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
412
Applicable Applications for anti-CTSD antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:3000
ELISA: 1:1000
Immunogen
The antiserum was produced against synthesized peptide derived from Internal of human CTSD.
Preparation and Storage
Store at-20 degree C for 1 year.

Testing Data

Testing Data
References
Faust P.L., Proc. Natl. Acad. Sci. U.S.A. 82:4910-4914(1985). Westley B.R., Nucleic Acids Res. 15:3773-3786(1987). Redecker B., DNA Cell Biol. 10:423-431(1991).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44,552 Da
NCBI Official Full Name
cathepsin D preproprotein
NCBI Official Synonym Full Names
cathepsin D
NCBI Official Symbol
CTSD
NCBI Official Synonym Symbols
CPSD; CLN10; HEL-S-130P
NCBI Protein Information
cathepsin D
UniProt Protein Name
Cathepsin D
Protein Family
UniProt Gene Name
CTSD
UniProt Synonym Gene Names
CPSD

NCBI Description

This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]

Uniprot Description

Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation (PubMed:27333034). Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

Research Articles on CTSD

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Product Notes

The CTSD ctsd (Catalog #AAA858341) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The CTSD Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CTSD can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:3000 ELISA: 1:1000. Researchers should empirically determine the suitability of the CTSD ctsd for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CTSD, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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