Rabbit GPR19 Polyclonal Antibody | anti-GPR19 antibody

GPR19 Polyclonal Antibody

Cat. Num. AAA3005896

• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunocytochemistry
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: GPR19; Polyclonal Antibody; GPR19 Polyclonal Antibody; Probable G-protein coupled receptor 19; GPR-NGA; anti-GPR19 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: GPR19 polyclonal antibody detects endogenous levels of GPR19 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 415

• Applicable Applications for anti-GPR19 antibody: Western Blot (WB), Immunocytochemistry (ICC)
• Application Notes: WB: 1:500-1:1000; ICC: 1:50-1:200
• Immunogen: Synthetic peptide, corresponding to amino acids 370-415 of Human GPR19.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of GPR19 polyclonal antibody at 1:500 dilutionLane1:Hela cell lysateLane2:NIH-3T3 cell lysateLane3:H9C2 cell lysate)

Related Product Information for anti-GPR19 antibody

G protein-coupled receptors (GPRs or GPCRs), also known as seven transmembrane receptors, heptahelical receptors, or 7TM receptors, are members of the largest protein family and play a role in many different stimulus-response pathways. G-protein coupled receptors mediate extracellular signals into intracellular signals (G-protein activation). They respond to a great variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GPR proteins are integral seven-pass membrane proteins with some conserved amino acid regions. GPR19, an orphan receptor, shows elevated expression during embyronic development of the nervous sytem as well as in specific regions of adult mouse brain, including the olfactory bulb, the hippocampus, hypothalamic nuclei and the cerebellum.

NCBI and Uniprot Product Information

• NCBI GI #: 5453666
• NCBI GeneID: 2842
• NCBI Accession #: NP_006134.1
• NCBI GenBank Nucleotide #: NP_006134.1
• UniProt Accession #: Q15760
• Molecular Weight: ~ 48kDa
• NCBI Official Full Name: probable G-protein coupled receptor 19
• NCBI Official Synonym Full Names: G protein-coupled receptor 19
• NCBI Official Symbol: GPR19
• NCBI Protein Information: probable G-protein coupled receptor 19
• UniProt Protein Name: Probable G-protein coupled receptor 19
• Protein Family: Probable G-protein coupled receptor
• UniProt Gene Name: GPR19
• UniProt Entry Name: GPR19_HUMAN

Uniprot Description

GPR19: Orphan receptor. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p12.3

Cellular Component: integral to plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway