Western Blot (WB)
(Figure 1. Western blot analysis using EBNA-3A anitbody on cell line infected with Epstein Barr virus.)
Sheep EBNA 3A Polyclonal Antibody | anti-EBNA 3A antibody
EBNA 3A
Applications
Western Blot
Purity
Ammonium Sulfate Precipitation
Synonyms
EBNA 3A; Polyclonal Antibody; EBNA3A; Epstein Barr Nuclear Antigen 3A; anti-EBNA 3A antibody
Host
Sheep
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Ammonium Sulfate Precipitation
Form/Format
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Sequence Length
925
Applicable Applications for anti-EBNA 3A antibody
Western Blot (WB)
Immunogen
The sheep antibody to EBMA-3A recognizes this antigen (MW 145 kDa) on an immunoblot of EBV infected cells (EBV +ve).
Positive Control
EBV infected tissues and cells
Preparation and Storage
Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
Western Blot (WB)
(Figure 1. Western blot analysis using EBNA-3A anitbody on cell line infected with Epstein Barr virus.)
Western Blot (WB)
(Figure 1. Western blot analysis using EBNA-3A anitbody on cell line infected with Epstein Barr virus.)
Related Product Information for anti-EBNA 3A antibody
EBNA-3A is a latent viral nuclear protein expressed in EBV transformed lymphoblastic cell lines. It is also found in some immunoblastic lymphomas in vivo. This viral nuclear protein is essential for EBV mediated transformation of B lymphocytes. The EBNA-3A functions as a transcriptional regulator though the target genes are currently unknown. Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop
Product Categories/Family for anti-EBNA 3A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
102.4
NCBI Official Full Name
EBNA-3A
NCBI Official Symbol
HHV4tp2_gp28
NCBI Protein Information
latency protein; EBNA-3A
UniProt Protein Name
Epstein-Barr nuclear antigen 3
UniProt Gene Name
EBNA3
UniProt Synonym Gene Names
EBNA-3; EBV nuclear antigen 3; EBNA-3A
UniProt Entry Name
EBNA3_EBVA8
Uniprot Description
Function: Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop
By similarity.
Subunit structure: Interacts with human UCKL1. Interacts with host CTPB1; this interaction seems important for EBNA3-mediated transcriptional repression. Interacts with host RBPJ
By similarity.
Subcellular location: Host nucleus matrix. Note: Associated with the nuclear matrix
By similarity.
Sequence similarities: Belongs to the herpesviridae EBNA-3 family.
Research Articles on EBNA 3A
Similar Products
Product Notes
The EBNA 3A ebna3 (Catalog #AAA395723) is an Antibody produced from Sheep and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's EBNA 3A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the EBNA 3A ebna3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EBNA 3A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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