Rabbit GPR15 Polyclonal Antibody | anti-GPR15 antibody

GPR15 Polyclonal Antibody

Cat. Num. AAA3005886

• Gene Names: GPR15; BOB
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunofluorescence
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: GPR15; Polyclonal Antibody; GPR15 Polyclonal Antibody; G-protein coupled receptor 15; Brother of Bonzo; BoB; GPR-15; anti-GPR15 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: GPR15 polyclonal antibody detects endogenous levels of GPR15 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 360

• Applicable Applications for anti-GPR15 antibody: Western Blot (WB), Immunofluorescence (IF)
• Application Notes: WB: 1:500-1:1000; IF: 1:50-1:200
• Immunogen: Synthetic peptide, corresponding to the 248-293 of Human GPR15.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of GPR15 polyclonal antibody at 1:500 dilutionLane1:Hela cell lysateLane2:Raw264. 7 cell lysateLane3:H9C2 cell lysate)

Related Product Information for anti-GPR15 antibody

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein-coupled receptors translate extracellular signals into intracellular signals (G protein-activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR15 (G protein-coupled receptor 15) is a 360 amino acid multi-pass membrane protein belonging to the G protein-coupled receptor 1 family. GPR15 is thought to function as a chemokine receptor and is encoded by a gene that maps to murine chromosome 16 C1.2.

NCBI and Uniprot Product Information

• NCBI GI #: 4885299
• NCBI GeneID: 2838
• NCBI Accession #: NP_005281.1
• NCBI GenBank Nucleotide #: NP_005281.1
• UniProt Accession #: P49685
• Molecular Weight: ~ 41kDa
• NCBI Official Full Name: G-protein coupled receptor 15
• NCBI Official Synonym Full Names: G protein-coupled receptor 15
• NCBI Official Symbol: GPR15
• NCBI Official Synonym Symbols: BOB
• NCBI Protein Information: G-protein coupled receptor 15
• UniProt Protein Name: G-protein coupled receptor 15
• Protein Family: G-protein coupled receptor
• UniProt Gene Name: GPR15
• UniProt Synonym Gene Names: BoB
• UniProt Entry Name: GPR15_HUMAN

NCBI Description

This gene encodes a G protein-coupled receptor that acts as a chemokine receptor for human immunodeficiency virus type 1 and 2. The encoded protein localizes to the cell membrane. [provided by RefSeq, Nov 2012]

Uniprot Description

GPR15: Probable chemokine receptor. Alternative coreceptor with CD4 for HIV-1 infection. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 3q11.2-q13.1

Cellular Component: integral to plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway