Western Blot (WB)
(Mouse Flt3 Antibody (N-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the Flt3 antibody detected the Flt3 protein (arrow).)
Rabbit Flt3 Polyclonal Antibody | anti-Flt3 antibody
Mouse Flt3 Antibody (N-term)
Western Blot (WB)
(Mouse Flt3 Antibody (N-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the Flt3 antibody detected the Flt3 protein (arrow).)
Western Blot (WB)
(Mouse Flt3 Antibody (N-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the Flt3 antibody detected the Flt3 protein (arrow).)
DeBoy, C.A., et al. Exp. Mol. Pathol. 89(2):109-116(2010)
Mkonyi, L.E., et al. Am. J. Physiol. Heart Circ. Physiol. 299 (2), H275-H283 (2010) :
Carotta, S., et al. Immunity 32(5):628-641(2010)
Eidenschenk, C., et al. Proc. Natl. Acad. Sci. U.S.A. 107(21):9759-9764(2010)
NCBI and Uniprot Product Information
Uniprot Description
FLT3: a receptor tyrosine kinase of the PDGFR family that binds the FL cytokine. FLT3 -/- mice have an impaired developmental capacity of primitive hematopoietic progenitor cells of all lineages with the greatest impact on lymphopoietic precursors. Activating mutations found in one third of cases of acute myeloid leukemia (AML), as well as in acute lymphoblastic leukemia, acute promyelocytic leukemia and myelodysplastic syndrome. Inhibitors: Sutent and PKC412.
Protein type: Protein kinase, TK; Oncoprotein; Kinase, protein; EC 2.7.10.1; Membrane protein, integral; Protein kinase, tyrosine (receptor); TK group; PDGFR family
Cellular Component: protein complex; cell surface; membrane; endoplasmic reticulum; cytoplasm; plasma membrane; integral to membrane; cytosol; nucleus; external side of plasma membrane
Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; nucleotide binding; transmembrane receptor protein tyrosine kinase activity; protein kinase activity; transferase activity; protein binding; protein-tyrosine kinase activity; ubiquitin protein ligase binding; transferase activity, transferring phosphorus-containing groups; protein complex binding; phosphoinositide 3-kinase binding; kinase activity; ATP binding; glucocorticoid receptor binding
Biological Process: negative regulation of B cell differentiation; lymphocyte proliferation; pro-B cell differentiation; peptidyl-tyrosine phosphorylation; protein amino acid autophosphorylation; cytokine and chemokine mediated signaling pathway; lymphoid progenitor cell differentiation; protein amino acid phosphorylation; negative regulation of cell proliferation; lymphocyte differentiation; myeloid progenitor cell differentiation; B cell differentiation; hemopoiesis; pro-T cell differentiation; positive regulation of protein amino acid phosphorylation; cell differentiation; phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; leukocyte homeostasis
Research Articles on Flt3
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Product Notes
The Flt3 flt3 (Catalog #AAA9202339) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 154-181. The Mouse Flt3 Antibody (N-term) reacts with Mouse (Predicted Reactivity: Human) and may cross-react with other species as described in the data sheet. AAA Biotech's Flt3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Flt3 flt3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Flt3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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