Western Blot (WB)
(Anti-Erbb3 Antibody (P1076)at 1:2000 dilution + mouse lung lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 148 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Rabbit anti-Mouse Erbb3 Polyclonal Antibody | anti-Erbb3 antibody
Mouse Erbb3 Antibody (P1076)
Western Blot (WB)
(Anti-Erbb3 Antibody (P1076)at 1:2000 dilution + mouse lung lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 148 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot (WB)
(Anti-Erbb3 Antibody (P1076)at 1:2000 dilution + mouse lung lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 148 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Moscoso L.M.,et al.Dev. Biol. 172:158-169(1995).
Kwon H.S.,et al.J. Biol. Chem. 288:26357-26371(2013).
NCBI and Uniprot Product Information
Uniprot Description
HER3: a receptor tyrosine kinase of the EGFR family. Binds and is activated by neuregulins and NTAK. Can form homodimers or ErbB-2/ErbB-3 heterodimers. Kinase domain lacks activity but heterodimerizes with other EGFRs to transduce growth signals. May be required for HER2 activity. Elevated expression in breast and other tumors is indicative of poor outcome. A secreted form is expressed in metastatic prostate cancer Two alternatively spliced isoforms have been described.
Protein type: Protein kinase, TK; Protein kinase, tyrosine (receptor); Membrane protein, integral; Oncoprotein; Kinase, protein; EC 2.7.10.1; TK group; EGFR family
Cellular Component: postsynaptic membrane; extracellular space; membrane; basolateral plasma membrane; apical plasma membrane; integral to membrane; nucleus; receptor complex; lateral plasma membrane
Molecular Function: identical protein binding; nucleotide binding; protein tyrosine kinase activator activity; receptor signaling protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase activity; protein kinase activity; transferase activity; protein binding; protein heterodimerization activity; growth factor binding; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; kinase activity; ATP binding
Biological Process: epidermal growth factor receptor signaling pathway; phosphoinositide 3-kinase cascade; cranial nerve development; negative regulation of cell adhesion; signal transduction; protein amino acid phosphorylation; regulation of cell proliferation; negative regulation of signal transduction; peripheral nervous system development; Schwann cell differentiation; positive regulation of glucose import; neuron apoptosis; negative regulation of secretion; negative regulation of neuron apoptosis; phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway
Research Articles on Erbb3
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Product Notes
The Erbb3 erbb3 (Catalog #AAA9204651) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Mouse Erbb3 Antibody (P1076) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Erbb3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:2000. Researchers should empirically determine the suitability of the Erbb3 erbb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Erbb3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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