Rabbit anti-Human ENTPD2 Polyclonal Antibody | anti-ENTPD2 antibody

ENTPD2 antibody

Cat. Num. AAA9411364

• Gene Names: ENTPD2; CD39L1; NTPDase-2
• Reactivity: Human
• Applications: Western Blot, Immunofluorescence
• Purity: Antibodies were purified by affinity purification using immunogen.
• Synonyms: ENTPD2; Polyclonal Antibody; ENTPD2 antibody; CD39L1; NTPDase-2; anti-ENTPD2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous level of total ENTPD2 antibody.
• Purity/Purification: Antibodies were purified by affinity purification using immunogen.
• Form/Format: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 472

• Applicable Applications for anti-ENTPD2 antibody: Western Blot (WB), Immunofluorescence (IF)
• Application Notes: Western blotting: 1:500 - 1:2000; Immunofluorescence: 1:50 - 1:100
• Immunogen Type: Recombinant Protein
• Immunogen Description: Recombinant protein of human ENTPD2.
• Target Name: ENTPD2
• Preparation and Storage: Store at -20 degree C

Immunofluorescence (IF)

(Immunofluorescence analysis of A549 cell using ENTPD2 antibody. Blue: DAPI for nuclear staining.)

Related Product Information for anti-ENTPD2 antibody

The protein encoded by this gene is the type 2 enzyme of the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). E-NTPDases are a family of ecto-nucleosidases that hydrolyze 5'-triphosphates. This ecto-ATPase is an integral membrane protein. Alternative splicing of this gene results in multiple transcript variants.

Product Categories/Family for anti-ENTPD2 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 4557421
• NCBI GeneID: 954
• NCBI Accession #: NP_001237.1
• NCBI GenBank Nucleotide #: NM_001246.3
• UniProt Accession #: Q9Y5L3; O15464; Q5SPY6; Q5SPY7
• Molecular Weight: 48,535 Da
• NCBI Official Full Name: ectonucleoside triphosphate diphosphohydrolase 2 isoform 2
• NCBI Official Synonym Full Names: ectonucleoside triphosphate diphosphohydrolase 2
• NCBI Official Symbol: ENTPD2
• NCBI Official Synonym Symbols: CD39L1; NTPDase-2
• NCBI Protein Information: ectonucleoside triphosphate diphosphohydrolase 2
• UniProt Protein Name: Ectonucleoside triphosphate diphosphohydrolase 2
• Protein Family: Ectonucleoside triphosphate diphosphohydrolase
• UniProt Gene Name: ENTPD2
• UniProt Synonym Gene Names: CD39L1; NTPDase 2; Ecto-ATPDase 2; Ecto-ATPase 2
• UniProt Entry Name: ENTP2_HUMAN

NCBI Description

The protein encoded by this gene is the type 2 enzyme of the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). E-NTPDases are a family of ecto-nucleosidases that hydrolyze 5'-triphosphates. This ecto-ATPase is an integral membrane protein. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Uniprot Description

ENTPD2: In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP. Belongs to the GDA1/CD39 NTPase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; Nucleotide Metabolism - purine; EC 3.6.1.-; Extracellular matrix; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 9q34

Cellular Component: endoplasmic reticulum membrane; integral to membrane; plasma membrane; basal lamina

Molecular Function: nucleoside-diphosphatase activity; nucleoside-triphosphatase activity; ATP binding

Biological Process: platelet activation; G-protein coupled receptor protein signaling pathway; purine ribonucleoside diphosphate catabolic process