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Immunohistochemistry (IHC) (Anti-ENTPD2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit ENTPD2 Polyclonal Antibody | anti-ENTPD2 antibody

Rabbit Polyclonal to Human ENTPD2

Gene Names
ENTPD2; CD39L1; NTPDase-2
Reactivity
Gorilla, Human
Predicted Reactivity: Monkey (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
ENTPD2; Polyclonal Antibody; Rabbit Polyclonal to Human ENTPD2; Anti-ENTPD2 Antibody (Internal) IHC-plus; CD39 antigen-like 1; Ecto-ATPDase 2; NTPDase 2; NTPDase-2; CD39L1; Ecto-ATP diphosphohydrolase 2; Ecto-ATPase 2; Human ENTPD2; anti-ENTPD2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Gorilla, Human
Predicted Reactivity: Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human ENTPD2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
472
Applicable Applications for anti-ENTPD2 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (2.5 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 18 amino acid peptide from internal region of human ENTPD2. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey, Marmoset (94%); Gibbon, Bovine (89%); Elephant, Panda (83%).
Immunogen Type
Synthetic peptide
Immunogen
ENTPD2 antibody was raised against synthetic 18 amino acid peptide from internal region of human ENTPD2. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey, Marmoset (94%); Gibbon, Bovine (89%); Elephant, Panda (83%).
Antigen Modification
Internal
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-ENTPD2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-ENTPD2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-ENTPD2 antibody
Similar to Gallus gallus ecto-ATPase and Homo sapiens lymphoid cell activation antigen CD39 which functions as an ectopyrase.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
954
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
48,535 Da
NCBI Official Full Name
ectonucleoside triphosphate diphosphohydrolase 2 isoform 2
NCBI Official Synonym Full Names
ectonucleoside triphosphate diphosphohydrolase 2
NCBI Official Symbol
ENTPD2
NCBI Official Synonym Symbols
CD39L1; NTPDase-2
NCBI Protein Information
ectonucleoside triphosphate diphosphohydrolase 2; NTPDase 2; ecto-ATPase 2; ecto-ATPDase 2; CD39 antigen-like 1; ecto-ATP diphosphohydrolase 2
UniProt Protein Name
Ectonucleoside triphosphate diphosphohydrolase 2
UniProt Gene Name
ENTPD2
UniProt Synonym Gene Names
CD39L1; NTPDase 2; Ecto-ATPDase 2; Ecto-ATPase 2
UniProt Entry Name
ENTP2_HUMAN

NCBI Description

The protein encoded by this gene is the type 2 enzyme of the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). E-NTPDases are a family of ecto-nucleosidases that hydrolyze 5'-triphosphates. This ecto-ATPase is an integral membrane protein. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Uniprot Description

ENTPD2: In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP. Belongs to the GDA1/CD39 NTPase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Extracellular matrix; Hydrolase; Membrane protein, integral; Membrane protein, multi-pass; EC 3.6.1.-; Nucleotide Metabolism - purine

Chromosomal Location of Human Ortholog: 9q34

Cellular Component: endoplasmic reticulum membrane; integral to membrane; plasma membrane; basal lamina

Molecular Function: nucleoside-diphosphatase activity; nucleoside-triphosphatase activity; ATP binding

Biological Process: G-protein coupled receptor protein signaling pathway; platelet activation; purine ribonucleoside diphosphate catabolic process

Research Articles on ENTPD2

Similar Products

Product Notes

The ENTPD2 entpd2 (Catalog #AAA244301) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human ENTPD2 reacts with Gorilla, Human Predicted Reactivity: Monkey (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's ENTPD2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (2.5 ug/ml). Researchers should empirically determine the suitability of the ENTPD2 entpd2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ENTPD2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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