Rabbit anti-Human ECEL1 Polyclonal Antibody | anti-ECEL1 antibody
ECEL1 Antibody
IF:1:50-1:200
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7046307 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human cervical cancer using MBS7046307 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunofluorescent analysis of HepG-2 cells using MBS7046307 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Immunofluorescence (IF)
(Immunofluorescent analysis of Hela cells using MBS7046307 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
ECEL1 polyclonal antibody MBS7046307 was produced in the rabbit immunized by using the Recombinant Human Endothelin-converting enzyme- like 1 protein (425-775AA) as the immunogen. The target protein ECEL1 is a member of the M13 family of endopeptidases. Members of this family are zinc- containing type II integral-membrane proteins that are important regulators of neuropeptide and peptide hormone activity. Diseases associated with ECEL1 include Arthrogryposis, Distal, Type 5D and Distal Arthrogryposis. This Rabbit anti-Homo sapiens (Human) ECEL1 Polyclonal antibody was tested in the IF, IHC and ELISA applications. The non-conjugated IgG got purified by protein G and reached up to 95% in purity. It only reacts with the ECEL1 proteins of human-origin and may be used to detect the endogenous levels of ECEL1 protein.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the M13 family of endopeptidases. Members of this family are zinc-containing type II integral-membrane proteins that are important regulators of neuropeptide and peptide hormone activity. Mutations in this gene are associated with autosomal recessive distal arthrogryposis, type 5D. This gene has multiple pseudogenes on chromosome 2. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]
Uniprot Description
ECEL1: May contribute to the degradation of peptide hormones and be involved in the inactivation of neuronal peptides. Belongs to the peptidase M13 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Protease; EC 3.4.24.-; Membrane protein, integral
Chromosomal Location of Human Ortholog: 2q37.1
Cellular Component: integral to plasma membrane
Molecular Function: metallopeptidase activity
Biological Process: respiratory system process
Disease: Arthrogryposis, Distal, Type 5d
Research Articles on ECEL1
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Product Notes
The ECEL1 ecel1 (Catalog #AAA7046307) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ECEL1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ECEL1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF). IHC:1:20-1:200 IF:1:50-1:200. Researchers should empirically determine the suitability of the ECEL1 ecel1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ECEL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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