Western Blot (WB)
(WB Suggested Anti-DYNC1I1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human brain)
Rabbit DYNC1I1 Polyclonal Antibody | anti-DYNC1I1 antibody
DYNC1I1 antibody - N-terminal region
Western Blot (WB)
(WB Suggested Anti-DYNC1I1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human brain)
Western Blot (WB)
(WB Suggested Anti-DYNC1I1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human brain)
Target Description: The aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. ALDH3B1 is highly expressed in kidney and lung.
NCBI and Uniprot Product Information
Uniprot Description
DYNC1I1: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150- glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores. Belongs to the dynein intermediate chain family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Microtubule-binding; Motor; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 7q21.3
Cellular Component: kinetochore; spindle pole; microtubule; recycling endosome; cytoplasmic dynein complex; perinuclear region of cytoplasm; cytosol; vesicle
Molecular Function: protein binding; spectrin binding; microtubule binding; motor activity; microtubule motor activity
Biological Process: metabolic process; vesicle transport along microtubule; antigen processing and presentation of exogenous peptide antigen via MHC class II
Research Articles on DYNC1I1
Similar Products
Product Notes
The DYNC1I1 dync1i1 (Catalog #AAA3210576) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DYNC1I1 antibody - N-terminal region reacts with Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DYNC1I1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the DYNC1I1 dync1i1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: GSQDSGDLGP LTRTLQWDTD PSVLQLQSDS ELGRRLHKLG VSKVTQVDFL. It is sometimes possible for the material contained within the vial of "DYNC1I1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
