Western Blot (WB)
(Western blot analysis of extracts of various tissues, using DLGAP5 antibody.)
Rabbit anti-Human DLGAP5 Polyclonal Antibody | anti-DLGAP5 antibody
DLGAP5 Antibody
Western Blot (WB)
(Western blot analysis of extracts of various tissues, using DLGAP5 antibody.)
Western Blot (WB)
(Western blot analysis of extracts of various tissues, using DLGAP5 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human stomach transfer using DLGAP5 antibody at dilution of 1:200 (x400 lens))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human stomach transfer using DLGAP5 antibody at dilution of 1:200 (x400 lens))
Immunofluorescence (IF)
(Immunofluorescence analysis of U2OS cell using DLGAP5 antibody. Blue: DAPI for nuclear staining.)
Immunofluorescence (IF)
(Immunofluorescence analysis of U2OS cell using DLGAP5 antibody. Blue: DAPI for nuclear staining.)
NCBI and Uniprot Product Information
Uniprot Description
DLG7: a cell cycle regulator that may play a role in carcinogenesis. Elevated levels of expression detected in the G2/M phase of synchronized cultures of HeLa cells. Required for chromosome congression and alignment. Stabilizes mitotic microtubules, promotes microtubule polymerization and controls spindle formation and dynamics Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Interacts with CDC2 and localizes to the spindle poles in mitotic cells. Interacts with the C-terminal proline-rich region of FBXO7. Recruited by FBXO7 to a SCF (SKP1-CUL1-F-box) protein complex in a CDC2/Cyclin B-phosphorylation dependent manner. Colocalizes with E-cadherin (CDH1) at sites of cell-cell contact in intestinal epithelial cells. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells. Two alternatively spliced isoforms have been described.
Protein type: Microtubule-binding; Cell cycle regulation
Chromosomal Location of Human Ortholog: 14q22.3
Cellular Component: cytoplasm; microtubule organizing center; spindle pole centrosome; nucleus
Molecular Function: protein binding; phosphoprotein phosphatase activity
Biological Process: cell proliferation; dephosphorylation; cell-cell signaling; positive regulation of mitotic metaphase/anaphase transition; mitotic chromosome movement towards spindle pole
Research Articles on DLGAP5
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Product Notes
The DLGAP5 dlgap5 (Catalog #AAA2528140) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DLGAP5 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DLGAP5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Researchers should empirically determine the suitability of the DLGAP5 dlgap5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DLGAP5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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