Rabbit anti-Human DGCR14 Polyclonal Antibody | anti-DGCR14 antibody

DGCR14, ID (DGCR14, DGCR13, DGSH, DGSI, ES2, Protein DGCR14, DiGeorge syndrome critical region 13, DiGeorge syndrome critical region 14, DiGeorge syndrome protein H, Protein ES2) (FITC)

Cat. Num. AAA6291852

• Gene Names: DGCR14; ES2; DGSH; DGSI; DGS-H; DGS-I; Es2el; DGCR13
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: DGCR14; Polyclonal Antibody; ID (DGCR14; DGCR13; DGSH; DGSI; ES2; Protein DGCR14; DiGeorge syndrome critical region 13; DiGeorge syndrome critical region 14; DiGeorge syndrome protein H; Protein ES2) (FITC); Protein ES2; anti-DGCR14 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-DGCR14 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: DGCR14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-244 amino acids from the Central region of human DGCR14.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(DGCR14 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the DGCR14 antibody detected the DGCR14 protein (arrow).)

Related Product Information for anti-DGCR14 antibody

This gene is located within the minimal DGS critical region (MDGCR) thought to contain the gene(s) responsible for a group of developmental disorders. These disorders include DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome, and some familial or sporadic conotruncal cardiac defects which have been associated with microdeletion of 22q11.2. The encoded protein may be a component of C complex spliceosomes, and the orthologous protein in the mouse localizes to the nucleus.

Product Categories/Family for anti-DGCR14 antibody

Antibodies; Disease Markers

References

Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). Olsen, J.V., et al. Cell 127(3):635-648(2006). Olsen, J.V., et al. Cell 127(3):635-648(2006). Wang, H., et al. J Neural Transm 113(10):1551-1561(2006). Jurica, M.S., et al. RNA 8(4):426-439(2002).

NCBI and Uniprot Product Information

• NCBI GI #: 126362976
• NCBI GeneID: 8220
• NCBI Accession #: NP_073210.1
• NCBI GenBank Nucleotide #: NM_022719
• UniProt Accession #: Q96DF8; Q49AH7; Q9BTZ4
• Molecular Weight: 52,568 Da
• NCBI Official Full Name: Homo sapiens DiGeorge syndrome critical region gene 14 (DGCR14), mRNA
• NCBI Official Synonym Full Names: DiGeorge syndrome critical region gene 14
• NCBI Official Symbol: DGCR14
• NCBI Official Synonym Symbols: ES2; DGSH; DGSI; DGS-H; DGS-I; Es2el; DGCR13
• NCBI Protein Information: protein DGCR14; DiGeorge syndrome critical region gene 13; DiGeorge syndrome critical region gene DGSI; DiGeorge syndrome gene H; DiGeorge syndrome gene I; Protein DGCR13; diGeorge syndrome critical region 13; diGeorge syndrome critical region 14; diGeorg
• UniProt Protein Name: Protein DGCR14
• Protein Family: Protein
• UniProt Gene Name: DGCR14
• UniProt Synonym Gene Names: DGCR13; DGSH; DGSI; ES2; DGS-H
• UniProt Entry Name: DGC14_HUMAN

NCBI Description

This gene is located within the minimal DGS critical region (MDGCR) thought to contain the gene(s) responsible for a group of developmental disorders. These disorders include DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome, and some familial or sporadic conotruncal cardiac defects which have been associated with microdeletion of 22q11.2. The encoded protein may be a component of C complex spliceosomes, and the orthologous protein in the mouse localizes to the nucleus. [provided by RefSeq, Jul 2008]